The effects of various modes of interval hypoxic training differing by the intensity and duration of hypoxic exposure on the morphology and antioxidant status of the heart and lung tissues were studied. Interval hypoxic training mode with more severe, but shorter hypoxic component led to the prooxidant/antioxidant imbalance in the myocardial and lung tissues, which was paralleled by significant disorders in their morphology and function. Moderate hypoxic exposure of different duration promoted the maintenance of optimum antioxidant homeostasis and development of compensatory adaptive changes in tissue structure.
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http://dx.doi.org/10.1007/s10517-007-0302-9 | DOI Listing |
Braz J Anesthesiol
January 2025
Zhongshan City People's Hospital, Department of Anesthesiology, Zhongshan, China.
Background: Extracorporeal Cardiopulmonary Resuscitation (ECPR) is an effective intervention for restoring adequate circulatory perfusion after cardiac arrest. Ensuring high-quality Cardiopulmonary Resuscitation (CPR) before initiating Extracorporeal Membrane Oxygenation (ECMO) is critical to mitigate tissue hypoxia and ischemia. This study aimed to evaluate the effect of End-Tidal Carbon Dioxide (ETCO) Goal-Directed CPR (GDCPR) on neurological function before ECMO using a retrospective case-control analysis.
View Article and Find Full Text PDFJ Neurophysiol
February 2025
Breathing Research and Therapeutics Center, Department of Physical Therapy, University of Florida, Gainesville, Florida, United States.
We present a case report of a 42-year-old female with post-West Nile virus meningoencephalitis who exhibited unique, long-latency diaphragm potentials evoked by transcranial and cervical magnetic stimulation after exposure to acute intermittent hypoxia (AIH). The subject was recruited for a study investigating AIH effects on respiratory motor function in healthy individuals. She had contracted West Nile virus infection 5 years before assessment that resulted in hospitalization and persistent allodynia but was not reported to the research team.
View Article and Find Full Text PDFAdv Neonatal Care
January 2025
Author Affiliations: Neonatal Intensive Care Unit, Seattle Children's Hospital, Seattle, WA (Mrs LaBella, Ms Kelly, Mrs Carlin, and Dr Walsh); and Seattle Children's Research Institute, Seattle, WA (Mrs Carlin and Dr Walsh).
Background: Finding an accurate and simple method of thermometry in the neonatal intensive care unit is important. The temporal artery thermometer (TAT) has been recommended for all ages by the manufacturer; however, there is insufficient evidence for the use of TAT in infants, especially to detect hypothermia.
Purpose: To assess the accuracy of the TAT in hypothermic neonates in comparison to a rectal thermometer.
Free Radic Res
January 2025
Institute of Sport Sciences, University of Lausanne, Lausanne, Suisse.
Little is known regarding the effects high-intensity training performed in hypoxia on the oxidative stress and antioxidant systems. The aim of this study was to assess the potential effect of 4 weeks of repeated sprint training in hypoxia (RSH) on the redox balance. Forty male well-trained cyclists were matched into two different interventions (RSH, = 20) or in normoxia, RSN, = 20) and tested twice (before (Pre-) and after (Post-) a 4-week of training) for performance (repeated sprint ability (RSA) test), oxidative stress, and antioxidant status.
View Article and Find Full Text PDFQuant Imaging Med Surg
January 2025
Department of Radiology, Qilu Hospital, Shandong University, Jinan, China.
Background: Hypoxia-inducible factor-1-alpha (HIF-1α) has the potential to predict the neoadjuvant chemotherapy (NAC) response in pancreatic ductal adenocarcinoma (PDAC). This study aimed to assess the relationship between the pathological response and intratumoral HIF-1α expression in patients with PDAC receiving NAC, and investigate the predictive value of contrast-enhanced computed tomography (CECT) features in HIF-1α expression.
Methods: A total of 58 patients from three centers with pathologically confirmed PDAC who underwent NAC followed by surgery were retrospectively enrolled in this study.
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