Introduction: Insulin adsorption onto infusion equipment may affect glycaemic control.
Methods: The change in insulin concentration during delivery through tubing employed for adult ICU and neonatal patients was determined using continuous flow UV analysis.
Results: Insulin adsorption depended on tubing composition, dimensions and flow rate, being highest for neonatal polyvinylchloride tubing at low flow rates.
Conclusion: In continuous insulin therapy, we should consider the nature of the infusion set and flow rate.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.diabres.2008.02.013 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
SERS-Based Aptamer Sensing Strategy for Diabetes Biomarker Detection.
Anal Chem
December 2024
Department of Chemistry, Institute for Molecular Science and Fusion Technology, Kangwon National University, Chuncheon 24341, Korea.
Accurate detection of glucose and insulin is crucial for early diagnosis, classification, and timely prevention of diabetes. In this study, we present a novel surface-enhanced Raman scattering (SERS) aptasensor for glucose and insulin detection. The SERS aptasensor is composed of gold bipyramidal nanoparticles (Au BPs), SH-aptamer-methylene blue (MB), and thiolated polyethylene glycol (SH-PEG).
View Article and Find Full Text PDFLignan-rich extract from Cinnamomum camphora leaf attenuates metabolic syndrome by modulating glycolipid metabolism and gut microbiota in T2DM mice.
Phytomedicine
December 2024
College of Life Sciences, Fujian Agriculture and Forestry University, Fuzhou 350002, China. Electronic address:
Background: Type 2 diabetes mellitus (T2DM) is a serious metabolic syndrome with high mortality and disability rates globally, which usually caused by unhealthy dietary patterns. Cinnamomum camphora leaf is a traditional Chinese medicinal herb used for attenuating hyperglycemia and digestive disorder, and high level of lignans has been found in C. camphora leaf.
View Article and Find Full Text PDFProteomic Analysis of Human Serum Proteins Adsorbed onto Collagen Barrier Membranes.
J Funct Biomater
October 2024
Department of Oral Biology, University Clinic of Dentistry, Medical University of Vienna, 1090 Vienna, Austria.
Collagen barrier membranes are frequently used in guided tissue and bone regeneration. The aim of this study was to analyze the signature of human serum proteins adsorbed onto collagen membranes using a novel protein extraction method combined with mass spectrometry. Native porcine-derived collagen membranes (Geistlich Bio-Gide, Wolhusen, Switzerland) were exposed to pooled human serum in vitro and, after thorough washing, subjected to protein extraction either in conjunction with protein enrichment or via a conventional surfactant-based method.
View Article and Find Full Text PDFBiological exposure to microplastics and nanoplastics and plastic additives: impairment of glycolipid metabolism and adverse effects on metabolic diseases.
Environ Sci Pollut Res Int
November 2024
College of Basic Medical Sciences, Guilin Medical University, Guilin, 541100, China.
Microplastics and nanoplastics (M-NPs) are widespread pollutants in the environment, posing growing risks to human health and garnering increasing concern from researchers. Due to their small particle size, ease of adsorption, and resistance to degradation, M-NPs can retain and migrate in the environment for long-term periods. Upon entering organisms, M-NPs have been reported to cause inflammation and oxidative stress and result in abnormalities in glycolipid metabolism.
View Article and Find Full Text PDFA Thin Polymer Layer Enables Peptide-Polycation Complexes with Ultrahigh Efficient Encapsulation.
Small
December 2024
Clinical Medical Research Center, Zhenjiang Hospital of Chinese Traditional and Western Medicine, Zhenjiang, 212004, China.
A monolayer encapsulation is a new opportunity for engineering a system with high drug loading, but immobilizing polymer molecules on the surface of individual peptide nanoparticles is still an ongoing challenge. Herein, an individual peptide nanoparticle encapsulation strategy is proposed via surface adsorption, in which peptide molecules undergo granulation and subsequently aggregate with polymer molecules, forming a network via electrostatic interactions. Under the water phase, surplus polymer molecules dissolve, leading to a single nanoparticle encapsulation with a core-shell structure.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!