The antigenic composition of tissues was shown to be of importance in the formation of bronchial asthma on the basis of the clinicoimmunological data with regard to histocompatibility antigens in 235 patients suffering from bronchial asthma and preasthma. Well-defined correlations were established between the development of bronchial asthma with carriership of antigens A2, B13, B21 and B35, between the disease pattern and nature of its course and antigens B7, B12, B27, B35, B40 together with their combinations. Possible variants of the relationship between the body traits and certain mechanisms by which bronchial asthma develops are under discussion.
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