The use of stem cells in the treatment of inoperable limb ischemia.

Perspect Vasc Surg Endovasc Ther

Division of Vascular Surgery, Northwestern University, Feinberg School of Medicine, Chicago, Illinois 60611, USA.

Published: March 2008

Autologous stem cell-based therapy offers many advantages over other nonsurgical treatments of peripheral arterial disease. Transplant stem cells are a renewable source of multiple cytokines and growth factors. Autologous adult stem cells are not rejected and do not form teratomas. Early preliminary results indicate that adult stem cell therapy is safe and effective in patients with critical limb ischemia.

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http://dx.doi.org/10.1177/1531003507313300DOI Listing

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