Prospects for a lossless negative dielectric constant material for optical devices are studied. Simulations show that with sufficient gain, a mixture of two semiconductor quantum dots (QDs) can produce an effective dielectric constant that is lossless and negative. This permits, in concept, arbitrarily small scaling of the optical mode volume, a major goal in the field of nanophotonics. The proposed implementation of a lossless negative dielectric constant material based on colloidal QDs opens a tractable path.
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PLoS One
December 2024
Faculty of Computer Science and Information Technology, Universiti Tun Hussein Onn Malaysia, Johor, Malaysia.
The rapid development of Digital Twin (DT) technology has underlined challenges in resource-constrained mobile devices, especially in the application of extended realities (XR), which includes Augmented Reality (AR) and Virtual Reality (VR). These challenges lead to computational inefficiencies that negatively impact user experience when dealing with sizeable 3D model assets. This article applies multiple lossless compression algorithms to improve the efficiency of digital twin asset delivery in Unity's AssetBundle and Addressable asset management frameworks.
View Article and Find Full Text PDFNanophotonics
March 2024
Department of Electrical and Computer Engineering, North Carolina State University, Raleigh, NC 27695, USA.
PeerJ Comput Sci
July 2024
CINBIO - Biomedical Research Centre, CINBIO, Vigo, Pontevedra, Spain.
With the advent and improvement of ontological dictionaries (WordNet, Babelnet), the use of synsets-based text representations is gaining popularity in classification tasks. More recently, ontological dictionaries were used for reducing dimensionality in this kind of representation (, Semantic Dimensionality Reduction System (SDRS) (Vélez de Mendizabal et al., 2020)).
View Article and Find Full Text PDFJ Am Soc Mass Spectrom
November 2024
Merck & Co., Inc., West Point, Pennsylvania 19486, United States.
Cyclic peptides are an important class of molecules that gained significant attention in the field of drug discovery due to their unique pharmacological characteristics and enhanced proteolytic stability. Yet, gastrointestinal degradation remains a major hurdle in the discovery of orally bioavailable cyclic peptides. Soft spot identification (SSID) of the regions in the cyclic peptide sequence susceptible to amide hydrolysis by proteases is used in the discovery stage to guide medicinal chemistry design.
View Article and Find Full Text PDFJ Proteome Res
May 2024
Central Hospital Affiliated to Shandong First Medical University, Jinan 250000, Shandong, China.
Several lossy compressors have achieved superior compression rates for mass spectrometry (MS) data at the cost of storage precision. Currently, the impacts of precision losses on MS data processing have not been thoroughly evaluated, which is critical for the future development of lossy compressors. We first evaluated different storage precision (32 bit and 64 bit) in lossless mzML files.
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