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Biomolecular condensates of Chlorocatechol 1,2-Dioxygenase as prototypes of enzymatic microreactors for the degradation of polycyclic aromatic hydrocarbons.
Int J Biol Macromol
June 2024
Laboratório de Biofísica Molecular, Departamento de Física, Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil. Electronic address:
Polycyclic aromatic hydrocarbons (PAHs) are molecules with two or more fused aromatic rings that occur naturally in the environment due to incomplete combustion of organic substances. However, the increased demand for fossil fuels in recent years has increased anthropogenic activity, contributing to the environmental concentration of PAHs. The enzyme chlorocatechol 1,2-dioxygenase from Pseudomonas putida (Pp 1,2-CCD) is responsible for the breakdown of the aromatic ring of catechol, making it a potential player in bioremediation strategies.
View Article and Find Full Text PDFWeeping sponge kidney: an unusual phenomenon that should be considered in cases of severe renal haemorrhage.
Clin Radiol
December 2023
Department of Radiology, St George's University Hospitals NHS Foundation Trust, Blackshaw Road, London SW17 0QT, UK.
Article Synopsis
- The study investigates multifocal renal capsular hemorrhage, also known as "weeping sponge kidney," focusing on its clinical features, imaging techniques, treatments, and outcomes while identifying risk factors and understanding the underlying mechanisms.
- The case series involved four patients, all treated successfully with embolization; three had chronic renal failure and atrophy, highlighting their association with this condition.
- The conclusion emphasizes that while small subcapsular hematomas typically resolve on their own, patients with renal failure face a higher risk of serious complications, necessitating different endovascular treatment strategies based on the number of bleeding points.
Association between Light-Induced Dynamic Dilation of Retinal Vessels and Echocardiographic Parameters of the Left Ventricular Function in Hypertensive Patients.
Medicina (Kaunas)
December 2020
First Department of Ophthalmology, Pomeranian Medical University in Szczecin, 70-111 Szczecin, Poland.
Background And Objectives: The goal was to evaluate the association of dynamic retinal vessel analysis (DVA) with echocardiographic parameters assessing systolic and diastolic function of the left ventricle in hypertension (HT) patients with preserved left ventricle ejection fraction.
Materials And Methods: This observational retrospective study recruited 36 patients with HT and 28 healthy controls. Retinal vessel diameter and reactions to flicker light were examined.
Using Artificial Intelligence to Predict Surgical Shunts in Men with Ischemic Priapism.
J Urol
November 2020
Department of Urology, Jackson Memorial Hospital and University of Miami Miller School of Medicine, Miami, Florida.
Purpose: Ischemic priapism is a urological emergency that requires prompt intervention to preserve erectile function. Characteristics that influence escalation to surgical intervention remain unclear. We identified factors and developed machine learning models to predict which men presenting with ischemic priapism will require shunting.
View Article and Find Full Text PDF[Granulomatous Prostatitis : Three Cases Report].
Hinyokika Kiyo
March 2019
The Department of Pathology, Saiseikai Noe Hospital.
Case 1 : A 65-year-old man visited withfrequent urination and dysuria. Pyuria and bacteriuria were observed and prostate specific antigen (PSA) was elevated to 5.69 ng/ml.
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