Data on porphyrin metabolism disturbances under the action of ionizing radiation on the human body are presented. The studies are based on estimating the quantitative content of coproporphyrin in the diurnal urine diuresis of persons irradiated as a result of the Chernobyl accident. The results of examining the population of a number of the zones of close control in Mogilev and Gomel Provinces are considered. Unlike the presumably healthy subjects, many people of this group show a significant decrease of porphyrin excretion with urine. The discovered sensitivity to the action of radiation is individual. A preliminary estimation of the porphyrin test depending on the degree of morphological changes in the gastric mucosa was made during an all-round clinical examination of the irradiated subjects.
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