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Clinical Manifestations.
Alzheimers Dement
December 2024
Yonsei University, Wonju, Gangwon-do, Korea, Republic of (South).
Background: Research on hemodynamic responses in the prefrontal cortex during working memory tasks has mainly been performed in cognitive neuroscience research. However, the specific stimuli contributing to working memory deficits in major depressive disorder (MDD) are currently lacking. This study aims to compare working memory performance and prefrontal cortex activation in individuals with MDD and healthy controls during working memory tasks involving textual, visual, and emotional stimuli.
View Article and Find Full Text PDFClinical Manifestations.
Alzheimers Dement
December 2024
First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.
Background: Individuals with mild cognitive impairment (MCI) commonly exhibit alterations in cortical structures accompanied by a mild decline in cognitive function. While the dual-task paradigm is utilized for MCI detection, its cortical mechanism remains incompletely understood. This study seeks to explore cortical structural changes and cognitive decline using the dual-task paradigm in individuals with MCI.
View Article and Find Full Text PDFClinical Manifestations.
Alzheimers Dement
December 2024
Vanderbilt University Medical Center, Nashville, TN, USA.
Background: Financial exploitation vulnerability (FEV) denotes the risk for falling victim to financial fraud and older adults reportedly lose an estimated $36 billion annually to scams. Socioemotional and cognitive impairments are potential risk factors for FEV in older adults with dementia. The present study examines whether the socioemotional measures of sensitivity to unfairness and self-unawareness of socioemotional dysfunction and brain atrophy are associated with increased risk for FEV in Alzheimer's disease (AD) and behavioral variant frontotemporal dementia (bvFTD).
View Article and Find Full Text PDFBackground: The application of image recognition technology has been spreading to dementia screening. However, cognitive function fluctuates due to mental and physical conditions. Therefore, we believe that it may be necessary to evaluate facial information over time after considering these factors.
View Article and Find Full Text PDFClinical Manifestations.
Alzheimers Dement
December 2024
Deparment of Developmental and Educational Psychology, University of Santiago de Compostela, Santiago de Compostela, Spain.
Background: Although there is evidence that measures of verbal fluency, naming and word memory can be good predictors of progression to dementia, language change and the main variables predicting it are not yet fully characterized. Recent research draws attention to the need to consider cognitive reserve, functional, and neurobiological indicators together to explain changes (Facal et al., 2021).
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