Acute myeloid leukaemia after treatment with (90)Y-ibritumomab tiuxetan for follicular lymphoma.

Hematol Oncol

Division of Hematology, Department of Oncology, Transplantations and New Technologies in Medicine, University of Pisa, Italy.

Published: September 2008

AI Article Synopsis

  • A patient with relapsed follicular lymphoma developed secondary acute myeloid leukemia 15 months after receiving radioimmunotherapy (RIT) with (90)Y-ibritumomab tiuxetan, marking the fifth known case of this occurrence.
  • Researchers examined existing literature to explore the potential link between RIT and the onset of secondary myelodysplastic syndromes or acute myeloid leukemia.
  • This case highlights the need for ongoing investigation into the long-term effects of RIT on patients and the risks of developing secondary cancers.

Article Abstract

We report here a patient with relapsed follicular lymphoma who developed secondary acute myeloid leukaemia 15 months after radioimmunotherapy (RIT) with (90)Y-ibritumomab tiuxetan, the fifth described case to date. We review the literature for the potential causal relationship between RIT and secondary myelodysplastic syndromes/acute myeloid leukaemia.

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Source
http://dx.doi.org/10.1002/hon.849DOI Listing

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