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Sequence-based Identification of Polyamine Oxidase Genes in Sorghum bicolor L.
Genome
January 2025
Damietta University Faculty of Science, New Damietta, Damietta, Egypt;
Polyamine oxidase (PAOs) are enzymes associated with polyamine catabolism and play important roles in growth and development and stress tolerance of plants. In the present study, genome-wide discovery and analysis of the PAO family in sorghum was done utilizing model PAO of Arabidopsis. Six PAO genes were found using publicly available genomic data.
View Article and Find Full Text PDFFirst-Line Mobocertinib Versus Platinum-Based Chemotherapy in Patients With Exon 20 Insertion-Positive Metastatic Non-Small Cell Lung Cancer in the Phase III EXCLAIM-2 Trial.
J Clin Oncol
January 2025
Department of Clinical Oncology, State Key Laboratory of Translational Oncology, Chinese University of China, Shatin, Hong Kong Special Administrative Region, China.
Purpose: Mobocertinib is an oral epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor that targets exon 20 insertion (ex20ins) mutations in non-small cell lung cancer (NSCLC). This open-label, phase III trial (EXCLAIM-2: ClinicalTrials.gov identifier: NCT04129502) compared mobocertinib versus platinum-based chemotherapy as first-line treatment of ex20ins+ advanced/metastatic NSCLC.
View Article and Find Full Text PDFDrying and storage of Piptadenia gonoacantha (Mart.) J.F.Macbr. seeds.
Braz J Biol
January 2025
Embrapa Agrobiologia, Seropédica, RJ, Brasil.
The objective was to evaluate the sensitivity of Piptadenia gonoacantha seeds to desiccation and storage conditions. The seeds were subjected to artificial drying in a forced air convection oven (39.7 °C ± 0.
View Article and Find Full Text PDFMorphometric characteristics of organs of female chickens (Pazo de Vilane) supplemented with Curcuma longa.
Braz J Biol
January 2025
Escuela Superior Politécnica de Chimborazo - ESPOCH, El Coca, Ecuador.
The breeding and exploitation of chickens at the backyard or commercial family level is an activity of great economic relevance for families in Ecuador. In addition to providing protein of high biological value for food security, it revalues local food resources that could provide productive benefits. With this objective, a study has been conducted in order to explore the effect of C.
View Article and Find Full Text PDFStudy of the role of transmembrane emp24 domain-containing protein 2 in oral squamous cell carcinoma.
J Appl Oral Sci
January 2025
Ningde Hospital Affiliated to Ningde Normal University, Department of Stomatology, Fujian, China.
Objective: This study aimed to investigate the role of transmembrane emp24 domain-containing protein 2 (TMED2) in oral squamous cell carcinoma (OSCC).
Methodology: A bioinformatics analysis was first conducted to explore TMED2 expression in OSCC and its relation with overall survival. The analysis results were further verified by assessing TMED2 expression levels in human normal oral keratinocyte cells and human OSCC cell lines using quantitative real-time polymerase chain reaction and the Western blot.
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