To identify correlates of epilepsy development in patients after brain injury, the authors carried out a comparative assessment of the spatial organization of brain electrical activity in patients with consequences of closed craniocerebral injury without epilepsy (53 patients) and in patients with post-traumatic epilepsy (43 patients). A control group included 15 subjects. The EEG study with spectral coherent analysis allows to predict post-traumatic epilepsy and to use a differential approach in prescribing the appropriate anticonvulsive therapy to people after head injury.
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Eur J Paediatr Neurol
January 2025
Dravet Syndrome UK, Chesterfield, UK.
Objectives: Dravet syndrome (DS) is a severe developmental and epileptic encephalopathy that requires significant caregiver input across the lifespan. This predominantly falls on parents, who are faced with considerable challenges including physical demands, financial burdens, and sustained pressure on mental wellbeing leading to mental health difficulties. We aimed to develop a grounded theory model for the process of coping and adjustment that occurs when caring for a child who has a diagnosis of DS.
View Article and Find Full Text PDFSeizure
December 2024
Epilepsy Center, Medical Center, University of Freiburg, Breisacher Str. 64, 79106 Freiburg im Breisgau, Germany.
Purpose: To evaluate the efficacy of cenobamate (CNB) in adults with focal epilepsy based on the number of previous lifetime antiseizure medications (ASMs).
Methods: Twenty patients receiving add-on treatment with CNB with <6 lifetime ASMs were retrospectively compared to 20 Patients with >10 ASMs and approximately the same age. Efficacy was assessed at 3, 6, and 12 months following CNB initiation.
Seizure
January 2025
Department of Neurology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China. Electronic address:
Objective: To translate and validate the Chinese version of the Epilepsy Anxiety Survey Instrument (EASI) and its brief version (brEASI) among Chinese people with epilepsy.
Methods: Adult outpatients from Sichuan Provincial People's Hospital were recruited. The type of anxiety disorder was determined via the Mini International Neuropsychiatric Interview (MINI).
Chaos
January 2025
Beijing Institute of Functional Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing 100053, China.
Generally, epilepsy is considered as abnormally enhanced neuronal excitability and synchronization. So far, previous studies on the synchronization of epileptic brain networks mainly focused on the synchronization strength, but the synchronization stability has not yet been explored as deserved. In this paper, we propose a novel idea to construct a hypergraph brain network (HGBN) based on phase synchronization.
View Article and Find Full Text PDFEur J Neurol
January 2025
Epilepsy Center, Department of Neurology, Fondazione IRCCS San Gerardo Dei Tintori, Monza, Italy.
Background: Epileptiform activity, including status epilepticus (SE), occurs in up to one-third of comatose survivors of cardiac arrest and may predict poor outcome. The relationship between SE and hypoxic-ischemic brain injury (HIBI) is not established.
Methods: This is a single-center retrospective study on consecutive patients with post-anoxic super-refractory SE.
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