We describe a case of recurring Candida glabrata infection in a 68-year-old African-American female on caspofungin therapy. The initial isolate was susceptible, but isolates recovered during following relapses were not. All isolates were clonal, and high-MIC strains contained a mutation in the highly conserved hot spot 1 region of Fks1p.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2415792 | PMC |
| http://dx.doi.org/10.1128/AAC.01568-07 | DOI Listing |
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