Mechanisms of macrolide resistance among Streptococcus pneumoniae isolates from Russia.

Antimicrob Agents Chemother

Institute for Medical Microbiology, National Reference Center for Streptococci, University Hospital (RWTH), Aachen, Germany.

Published: June 2008

Among 76 macrolide-nonsusceptible Streptococcus pneumoniae isolates collected between 2003 and 2005 from Central Russia, the resistance mechanisms detected in the isolates included erm(B) alone (50%), mef alone [mef(E), mef(I), or a different mef subclass; 19.7%], or both erm(B) and mef(E) (30.3%). Isolates with dual resistance genes [erm(B) and mef(E)] belonged to clonal complex CC81 or CC271.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2415785PMC
http://dx.doi.org/10.1128/AAC.01270-07DOI Listing

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