Severity: Warning
Message: file_get_contents(https://...@pubfacts.com&api_key=b8daa3ad693db53b1410957c26c9a51b4908&a=1): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
Filename: helpers/my_audit_helper.php
Line Number: 176
Backtrace:
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 176
Function: file_get_contents
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 250
Function: simplexml_load_file_from_url
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 1034
Function: getPubMedXML
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 3152
Function: GetPubMedArticleOutput_2016
File: /var/www/html/application/controllers/Detail.php
Line: 575
Function: pubMedSearch_Global
File: /var/www/html/application/controllers/Detail.php
Line: 489
Function: pubMedGetRelatedKeyword
File: /var/www/html/index.php
Line: 316
Function: require_once
Blood damage and platelet activation are inherent problems with present day mechanical heart valve designs. We investigate the approach of passive flow control applied to bileaflet mechanical heart valve (BMHV) flows as a means of optimizing leakage flow hemodynamics at length scales relevant to blood damage and platelet activation. Rectangular and hemispherical vortex generator (VG) arrays were mounted on the downstream surfaces of a 25 mm St. Jude Medical valve adjacent to the b-datum leaflet edge (central line where the two leaflets touch in closed position). The effect of VGs on the flow structure emanating from the b-datum line under both pulsatile and steady flow conditions was measured using high resolution particle image velocimetry technique. The VGs were seen to spatially disperse and dissipate the coherent leakage jet structure emanating from the b-datum line. This resulted in a significant diminution of turbulence stresses, particularly with the rectangular VG configuration. This study shows that passive flow control techniques deployed on BHMVs is potentially beneficial as significant control of flow at small length scales may be achieved without altering large scale designs of the valve.
Download full-text PDF |
Source |
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http://dx.doi.org/10.1016/j.jbiomech.2008.01.024 | DOI Listing |
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