Paraneoplastic hypertension associated with a renal oncocytoma is an unreported syndrome. We report a unique case of a patient with multidrug-resistant hypertension who was found to have a solitary renal mass. Cryoablation was performed and resulted in an immediate and dramatic decrease in blood pressure. Histologic review of intraoperative biopsy specimens revealed findings consistent with renal oncocytoma. To our knowledge, this is the first report of hypertension in the setting of a renal oncocytoma, with subsequent improvement of this paraneoplastic syndrome after cryoablation.
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- * They typically appear as well-defined, tan or mahogany masses with a central scar, and their histology features simple cell structures that indicate low malignancy risk.
- * A review of 17 studies showed that while there is potential for metastasis (to liver, bones, lungs), only 1.5% experienced disease progression, indicating that aggressive cancer behavior is not necessarily linked to oncocytomas.
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