The camera onboard the Cassini spacecraft has allowed us to observe many of Saturn's cloud features. We present observations of Saturn's south polar vortex (SPV) showing that it shares some properties with terrestrial hurricanes: cyclonic circulation, warm central region (the eye) surrounded by a ring of high clouds (the eye wall), and convective clouds outside the eye. The polar location and the absence of an ocean are major differences. It also shares properties with the polar vortices on Venus, such as polar location, cyclonic circulation, warm center, and long lifetime, but the Venus vortices have cold collars and are not associated with convective clouds. The SPV's combination of properties is unique among vortices in the solar system.
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http://dx.doi.org/10.1126/science.1153633 | DOI Listing |
Immunotherapy
September 2024
Legorreta Cancer Center at Brown University, Lifespan Cancer Institute, Providence, RI 02903,USA.
This first-in-human study evaluated safety and efficacy of CD40 agonist MEDI5083 with durvalumab in patients with advanced solid tumors. Patients received MEDI5083 (3-7.5 mg subcutaneously every 2 weeks × 4 doses) and durvalumab (1500 mg every 4 weeks) either sequentially (N = 29) or concurrently (N = 9).
View Article and Find Full Text PDFNat Commun
August 2024
Laboratoire de Planétologie et Géosciences, UMR 6112, Nantes Université, Univ Angers, Le Mans Université, CNRS, Nantes, France.
After discovering a jet activity near the south pole of Saturn's moon Enceladus, the Cassini mission demonstrated the existence of a subsurface water ocean with a unique sampling opportunity through flybys. Diurnal variations in the observed brightness of the plume suggest a tidal control, although the existence and timing of two activity maxima seem to contradict stress analysis predictions. Here, we re-interpret the observed plume variability by combining a 3D global model of tidal deformation of the fractured ice shell with a 1D local model of transport processes within south-polar faults.
View Article and Find Full Text PDFTraditional heat health warning systems focus on severe and extreme heat events at the district or regional level, often overlooking localized risk and protective factors such as healthcare access and urban green spaces. This approach considers less the varying impacts of heat within cities, including the phenomenon of Urban Heat Islands (UHIs) and the diverse needs of different populations. To address these shortcomings, a need for the development of an Urban Heat Health Warning and Information System (UHHWIS) that operates within the framework of Heat Health Action Plans is needed.
View Article and Find Full Text PDFJ Environ Manage
June 2024
Bioengineering Laboratory, Higher School of Biotechnology, Ville Universitaire Ali Mendjeli, BP E66, 25100, Constantine, Algeria.
Amoxicillin, a member of the penicillin family, is primarily utilized for the treatment of various bacterial infections affecting ears, nose, throat, urinary tract, and skin. Given its widespread application in medicine, agriculture, environment, and food industry, the precise and sensitive detection of amoxicillin is important. This study introduces a novel approach to developing a sensitive and selective fluorescent aptasensor relying on fluorescence resonance energy transfer (FRET) for the specific detection of amoxicillin.
View Article and Find Full Text PDFJ Craniomaxillofac Surg
January 2024
Yonsei University, Plastic & Reconstructive Surgery, Seoul, South Korea; Institute for Human Tissue Restoration, Seoul, South Korea. Electronic address:
This study aimed to analyze the anatomical differences in levator aponeurosis angle and length between both sides in double eyelidplasty in East Asians. The retrospective study included patients with mild blepharoptosis who underwent upper blepharoplasty with levator aponeurosis. In the study, 140 patients were enrolled, 126 females and 14 males, with an age range of 16-73 years.
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