The efficiency of using prolonged venovenous hemofiltration (PVVH) was studied in 12 children with severe thermal injury in the presence of multiple organ dysfunctions. All the children were critically ill (having artificial ventilation, inotropic support, states of coma, renal dysfunction) and received the whole package of intensive care measures. Five of the 12 children were diagnosed as having sepsis, as verified by the procalcitonin ( >10 ng/ml) test. All the patients received 2 to 10 sessions PVVH on a PRIZMA apparatus ("Gambra", Sweden). Five of the 12 children died; the remaining children were observed to feel better; they were all transferred to somatic units. Thus, PWVVH is the method of choice in complex therapy for severe thermal injury followed by the development of multiple organ dysfunctions.

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