AI Article Synopsis
- Coagulase-negative staphylococci (CNS) are significant contributors to infective endocarditis (IE), yet their microbiological characteristics remain inadequately understood.
- A study involved DNA sequencing and susceptibility testing of samples from 91 patients with confirmed CNS IE, revealing considerable genetic diversity among strains across different geographic regions.
- The analysis of rpoB gene sequences highlighted unique genetic markers that could be valuable for global monitoring of CNS infections.
Article Abstract
Coagulase-negative staphylococci (CNS) are important causes of infective endocarditis (IE), but their microbiological profiles are poorly described. We performed DNA target sequencing and susceptibility testing for 91 patients with definite CNS IE who were identified from the International Collaboration on Endocarditis-Microbiology, a large, multicenter, multinational consortium. A hierarchy of gene sequences demonstrated great genetic diversity within CNS from patients with definite endocarditis that represented diverse geographic regions. In particular, rpoB sequence data demonstrated unique genetic signatures with the potential to serve as an important tool for global surveillance.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2395089 | PMC |
| http://dx.doi.org/10.1128/JCM.02405-07 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!