AI Article Synopsis
- Kawasaki disease (KD) is now the leading cause of acquired heart disease in children in developed countries.
- The exact cause of KD is still unclear, but researchers suspect an unidentified infectious agent may be involved.
- New findings about IgA responses to specific structures in KD tissues could help reveal the underlying cause and enhance diagnosis and treatment options.
Article Abstract
Kawasaki disease (KD) has emerged as the most common cause of acquired heart disease in children in the developed world. The cause of KD remains unknown, although an as-yet unidentified infectious agent might be responsible. By determining the causative agent, we can improve diagnosis, therapy and prevention of KD. Recently, identification of an antigen-driven IgA response that was directed at cytoplasmic inclusion bodies in KD tissues has provided new insights that could unlock the mysteries of KD.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7097362 | PMC |
| http://dx.doi.org/10.1038/nrmicro1853 | DOI Listing |
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