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Cannabidiol for Scan-Related Anxiety in Women With Advanced Breast Cancer: A Randomized Clinical Trial.
JAMA Netw Open
December 2024
Department of Supportive Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
Importance: Early evidence from studies outside of oncology has suggested that cannabidiol (CBD) may have anxiolytic effects without neuropsychiatric risks. An understanding of oral CBD in patients with cancer-related anxiety is urgently needed.
Objective: To determine whether a single 400-mg oral dose of a US Food and Drug Administration-approved CBD improves clinical anxiety in an oncologic population.
Randomised controlled trial of HOYA one-day multifocal contact lenses: The HOMCL trial.
Heliyon
November 2024
HOYA Vision Care, Radarweg 29, 1043 NX, Amsterdam, the Netherlands.
Trial Design: Double-masked crossover RCT (Research Registry: #8136) comparison of a new HOYA one-day disposable multifocal contact lens (HOMCL) with Alcon DAILIES TOTAL1® Multifocal (ADT1).
Methods: Sixty presbyopic participants from three countries attended for baseline measurements and fitting of both lens types and then for a fortnight completed daily diaries of symptoms with habitual optical correction, and VF-14 questionnaire. Participants collected either HOMCL or ADT1, when the vision was measured again, and they wore this product for a fortnight, completing daily diaries and VF-14.
May dental implant macro and microgeometry modifications influence peri-implant bone repair in smokers? A randomized clinical trial.
BMC Oral Health
December 2024
Departamento de Odontologia, Universidade Paulista (UNIP), Av. Dr. Bacelar, 1212, Vila Clementino, São Paulo, 04026-002, Brazil.
Background: This split-mouth, double-masked, randomized clinical trial aimed at evaluating the impact of different macro geometries and nano topographical modifications on peri-implant bone repair in smokers.
Methods: Thirty-two patients who smoked at least ten cigarettes/day, with the need of a single maxillary or mandibular implant bilaterally, received two implants randomly assigned to DA - Dual Acid-Etched implants (n = 32); HCAN - healing chambers and activated nano surface (n = 32). Implant stability quotient (ISQ) was evaluated 07, 30, 60, 90, and 120 days after implant placement.
Slowing myopia progression with cylindrical annular refractive elements (CARE) spectacle lenses-Year 1 results from a 2-year prospective, multi-centre trial.
Acta Ophthalmol
November 2024
ZEISS Vision Care, Aalen, Germany, Carl Zeiss Vision International GmbH, Aalen, Germany.
Purpose: To evaluate the effectiveness of 12 months of spectacle lens wear incorporating cylindrical annular refractive elements (CARE) in slowing myopia progression compared to single vision (SV) spectacle wear.
Methods: In an ongoing 2-year prospective, double-masked, multi-centre clinical trial, 240 Chinese children aged 6-13 years, spherical equivalent refractive error (SE) -0.75 D to -5.
Glaucoma Rehabilitation Using ElectricAI Transcranial Stimulation (GREAT)-Optimizing Stimulation Protocol for Vision Enhancement Using an RCT.
Transl Vis Sci Technol
September 2024
School of Optometry, The Hong Kong Polytechnic University, Hong Kong SAR, China.
Article Synopsis
- The study assessed the effects of three types of transcranial electrical stimulation (tES) on peripheral vision in glaucoma patients using a double-masked, placebo-controlled approach with 35 participants.
- Results showed that anodal transcranial direct current stimulation (a-tDCS) significantly improved visual detection accuracy and electrophysiological measures (signal-to-noise ratio and latency) compared to sham stimulation, while other tES methods (tACS and tRNS) did not show significant improvements.
- The findings indicate a-tDCS can enhance vision measures in glaucoma patients, but the overall changes observed were minimal, suggesting further research is needed to explore its effectiveness.
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