[Validation of Polish version of CFQoL in patients with cystic fibrosis].

Unlabelled: Cystic Fibrosis Quality of Life Questionnaire (CFQoL), is a specific measurement tool of quality of life in adolescents and adults with cystic fibrosis, fully verified in English-speaking countries. However, introduction of new language version requires validation process. The aim of this study was to validate Polish version of CFQoL questionnaire.

Material And Methods: Language adaptation was performed after obtaining consent of the author. Healthy group (n=40, mean age = 19.5 +/- 3.4 years) assessed level of comprehension of each questionnaire item. Final Polish version of the questionnaire was assessed in 33 patients with cystic fibrosis (mean age = 21.8 +/- 3.4 years). The comparisons included CFQoL, SGRQ, WHOQOL-BREF, HADS and medical records analysis (spirometry, Shwachman-Kulczycki scale).

Results: CFQoL questionnaire was well understood and its graphics and time of completion were highly assessed. Good reliability of CFQoL was proven: Cronbach's Alpha coefficient was over 0.7 for all subscales, and high correlations between each item and general outcome for every subscale were found (r = from 0.63 to 0.93; p < 0.001). High correlation was observed in measurements repeated after 3 to 4 days (r = from 0.66 to 0.93; p < 0.001), the only difference between assessments was reduction of concerns about future (p = 0.007). Accuracy of the questionnaire was proven by significant correlations between CFQoL subscale assessing physical functioning and general outcome of SGRQ, psychosocial aspect of CFQoL and WHOQOL-BREF subscales, and emotional functioning subscale of CFQoL and anxiety and depression in HADS scale. There were no relationship between clinical data and CFQoL except Shwachman-Kulczycki scale.

Conclusion: Polish version of the questionnaire fulfilled basic psychometric criteria and may be used for evaluation of quality of life of adolescents and adults with cystic fibrosis.