To what extent should we lower HbA1c in diabetic subjects?

Diabetes Metab

CHU de Poitiers, Department of Endocrinology Diabetology, 2, rue de la Milètrie, BP 577, 86021 Poitiers cedex, France.

Published: February 2008

Current recommendations regarding glycemic control suggest that HbA(1c) should be lower than 6.5%. This is supported by data regarding microvascular disease, namely retinopathy rather than nephropathy. The question is not completely solved regarding cardiovascular diseases, where a strategy of very low HbA(1c) ("the lower the better") is expected to be effective. Some ongoing studies will help to answer these unsolved questions.

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http://dx.doi.org/10.1016/S1262-3636(08)70102-2DOI Listing

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