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Overcrowding in prisons: Health and legal implications.
Torture
January 2025
Medical Director, DIGNITY. Correspondence to:
Introduction: Prison overcrowding can be defined in different ways, and no universal definition exists. More than 120 countries report prison occupancy rates above their own capacity. This paper provides an overview of legal and health implications of overcrowding, analyses potential causes, and provides examples of how different countries utilised non-custodial measures to reduce overcrowding to disseminate good practices as inspiration for other contexts.
View Article and Find Full Text PDFThe role of rodent behavioral models of schizophrenia in the ongoing search for novel antipsychotics.
Expert Opin Drug Discov
January 2025
Centro de Investigación en Reproducción Animal, Universidad Autónoma de Tlaxcala - CINVESTAV Tlaxcala, Tlaxcala, México.
Introduction: Existing pharmacotherapies for schizophrenia have not progressed beyond targeting dopamine and serotonin neurotransmission. Rodent models of schizophrenia are a necessary tool for elucidating neuropathological processes and testing potential pharmacotherapies, but positive preclinical results in rodent models often do not translate to positive results in the clinic.
Areas Covered: The authors reviewed PubMed for studies that applied rodent behavioral models of schizophrenia to assess the antipsychotic potential of several novel pharmacotherapies currently under investigation.
The escape room: will we be able to build a team?
Intern Emerg Med
January 2025
Center for Advanced Simulation in Medicine, University Hospital Careggi, Lg. Brambilla 3, 50134, Florence, Italy.
A multi-person reflection on using public and patient involvement and engagement to develop dementia research.
Res Involv Engagem
January 2025
, Suffolk, UK.
Involving people living with dementia in the development of research through PPIE is the gold standard for ethical research. Established PPIE groups have been set up throughout the UK to provide people with dementia opportunities to have their voice heard. However, accessing these groups as a doctoral researcher can be difficult, and little guidance is given on how to make the process successful.
View Article and Find Full Text PDFDynamic structural characteristics and vibration susceptibility of Tongren loess under the influence of water content and confining pressure.
Sci Rep
January 2025
Institute of Geomechanics, Chinese Academy of Geological Sciences, Beijing, 100081, China.
Loess is extensively developed on both sides of the Longwu River, a tributary of the Yellow River, Tongren County, Qinghai Province. The engineering geological characteristics are complex, and landslide disasters are highly developed. Based on field geological surveys and physical property analysis of the loess in this area, this study analyzes the influence of water content, consolidation pressure, and soil disturbance on the dynamic characteristics of loess using GDS dynamic triaxial tests.
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