The aim of this study was to evaluate the incidence of abnormal muscular bands of the anterior compartment of the arm that may compress the median, the ulnar, and the medial antebrachial cutaneous nerve as well as the brachial artery and vein, thus causing entrapment at and above the elbow. A total of 56 adult cadavers were studied during routine dissections that occurred in our laboratory. In the 112 upper limbs studied, we found three variant muscles of the flexor compartment of the arm (2.68%) entrapping nerves and vessels. The first muscle was emerging from the tendon of long head of biceps brachii and coracobrachialis muscle insertion. The second muscle inserted partially into the belly of biceps brachii and should be considered as a supernumenary head of biceps brachii. The third muscle, in fact, represents an accessory fascicle of the brachialis muscle that is an embryonic remnant of that muscle. A number of structures cross anterior to the median, ulnar, and medial antebrachial cutaneous nerve as well as the brachial artery and vein. Compression of nerves and vessels may be caused by additional muscular bundles that pass anterior to these structures. These additional muscular bundles arise either from the brachialis, coracobrachialis, or biceps brachii muscle. Such variations have clinical implications and should be considered in patients, with a high median or ulnar or medial antebrachial cutaneous nerve paralysis with symptoms of lower brachial artery or brachial vein compression.

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