The 3-dimensional forces exerted on an abutment tooth of a removable partial denture (RPD) were measured in vivo during clenching using a force-measuring device with a piezoelectric transducer. The device was mounted on the mandibular right second premolar of a subject with an edentulous maxilla. The magnitude of the forces was higher and the direction was more posterior without the RPD in place. The direction was most posterior with an RPD with a distal rest only and most anterior with an RPD with a mesial rest only. The 3-dimensional forces exerted on an abutment tooth thus depend on both the presence of a denture and the rest location.
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Neurochem Int
December 2024
School of Medicine, Fu Jen Catholic University, New Taipei City 24205, Taiwan; Research Center for Chinese Herbal Medicine, College of Human Ecology, Chang Gung University of Science and Technology, Taoyuan City 33303, Taiwan. Electronic address:
Hydrogen gas (H) is an antioxidant with demonstrated neuroprotective efficacy. In this study, we administered H via inhalation to rats to evaluate its effects on seizures induced by kainic acid (KA) injection and the underlying mechanism. The animals were intraperitoneally injected with KA (15 mg/kg) to induce seizures.
View Article and Find Full Text PDFMethods Mol Biol
December 2024
Department of Biomedical Engineering, The Chinese University of Hong Kong, Hong Kong, China.
Mitochondria are dynamic organelles with constantly changing morphologies. Despite recent reports indicating that mechanical cues modulate mitochondrial morphologies and functions, there is a lack of methods that can exclusively and precisely exert mechanical forces to and deform mitochondria in live cells. Therefore, how mitochondria sense and respond to mechanical forces remains largely elusive.
View Article and Find Full Text PDFInteractions between magma oceans and overlying atmospheres on young rocky planets leads to an evolving feedback of outgassing, greenhouse forcing, and mantle melt fraction. Previous studies have predominantly focused on the solidification of oxidized Earth-similar planets, but the diversity in mean density and irradiation observed in the low-mass exoplanet census motivate exploration of strongly varying geochemical scenarios. We aim to explore how variable redox properties alter the duration of magma ocean solidification, the equilibrium thermodynamic state, melt fraction of the mantle, and atmospheric composition.
View Article and Find Full Text PDFJ Chromatogr A
December 2024
Department "Area Materno-Infantile" Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan Italy.
Gravitational Field-Flow Fractionation (GrFFF) is an elution-based method designed for the separation of particles ranging from a few micrometers up to approximately 100 μm in diameter. Separation occurs over time, with particles being fractionated based on size and other physico-chemical properties. GrFFF takes advantage of gravitational forces acting perpendicularly to a laminar flow in a thin channel.
View Article and Find Full Text PDFFront Bioeng Biotechnol
December 2024
Karl Chiari Lab for Orthopaedic Biology, Department of Orthopedics and Trauma Surgery, Medical University of Vienna, Vienna, Austria.
Biomechanical (over-)stimulation, in addition to inflammatory and fibrotic stimuli, severely impacts the biology, contributing to the overall chronic nature of desmopathy. A major challenge has been the lack of representative two-dimensional (2D) models mimicking inflammatory processes in the presence of dynamic mechanical strain, both being crucial for ligament homeostasis. Physiological levels of strain exert anti-inflammatory effects, while excessive strain can facilitate inflammatory mechanisms.
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