Aim: At University Department of Orthopedic Surgery in Lovran, bone bank was established in 1985 for preserving and storage of musculoskeletal tissue. At first, storage was only done for femoral heads as surgical residues of hip replacement. Since 1993, storage is also done for transplants obtained by retrieving bone allografts from cadavers during multiorgan explantations.
Methods: Transplant donors are chosen on the basis of medical history, physical examination and laboratory analysis of blood samples. Transplants are kept at the bone bank, by deep freeze method, at temperature of -80 degrees C.
Results: During the 2002-2006 period, bone bank delivered a total of 729 bone allografts, which were succesfully used in surgical treatment.
Conclusion: Good results of the surgeries using bone allografts stimulated us for further development of bone banking.
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J Paleolit Archaeol
July 2024
Laboratory of Theriology, Zoological Institute of the Russian Academy of Sciences, St. Petersburg, Russian Federation.
The Altai mountains contain a number of cave and rockshelter sites that have given crucial information about human evolution in Asia. Most of these caves are located in the Gornyi Altai of Siberia, while the southern flank of the range remains much less known. Bukhtarma Cave was a karstic cave located near the former village of Peshchera, on the banks of the Bukhtarma River running through the foothills of the southern (Kazakh) Altai mountains.
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University/BHF Centre for Cardiovascular Science, University of Edinburgh, The Queen's Medical Research Institute, Edinburgh BioQuarter, 47 Little France Crescent, Edinburgh, UK.
Bone marrow adipose tissue is a distinct adipose subtype comprising more than 10% of fat mass in healthy humans. However, the functions and pathophysiological correlates of this tissue are unclear, and its genetic determinants remain unknown. Here, we use deep learning to measure bone marrow adiposity in the femoral head, total hip, femoral diaphysis, and spine from MRI scans of approximately 47,000 UK Biobank participants, including over 41,000 white and over 6300 non-white participants.
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December 2024
Laboratory of Regional Center of Excellence for Poultry Science, University of Lomé, 01 BP 1515, Lomé, Togo.
The present study examined the effects of breeder age and oxygen (O₂) concentrations during the late chorioallantoic membrane (CAM) growth stage on embryo development, hatching dynamics, chick quality, bone mineralization and hatchability. A total of 1200 eggs from 33- and 50-week-old ISA layer breeders, weighing 53.85 g and 60.
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December 2024
Department of Laboratory Hematology and Blood Bank, School of Allied Medical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Introduction: Despite advances in the treatment of acute myeloid leukemia (AML), refractory forms of this malignancy and relapse remain common. Therefore, development of novel, synergistic targeted therapies are needed urgently. Recently, mesenchymal stem cells (MSCs) have been shown to be effective in treating various diseases, with most of their therapeutic outcomes attributed to their exosomes.
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January 2025
Department of Biomaterials, Institute of Clinical Dentistry, Faculty of Dentistry, University of Oslo, Oslo, Norway.
The eggshell membrane (ESM), resembling the extracellular matrix (ECM), acts as a protective barrier against bacterial invasion and offers various biofunctions due to its porous structure and protein-rich composition, such as ovalbumin, ovotransferrin, collagen, soluble protein, and antimicrobial proteins. However, the structure of ESM primarily comprises disulfide bonds and heterochains, which poses a challenge for protein solubilization/extraction. Therefore, the method of dissolving and extracting bioactive protein components from ESM has significant potential value and importance for exploring the reuse of egg waste and environmental protection.
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