[Study on changes of CT performance and pulmonary function in renal transplant recipients with pneumocystis pneumonia].

Objective: To investigate dynamic changes of CT performance and pulmonary function in renal transplant recipients with pneumocystis pneumonia.

Methods: A retrospective analysis was made upon the clinic data of chest CT, arterial blood gas and pulmonary function in renal transplant recipients with pneumocystis pneumonia from 2002 to 2006 in the first affiliated hospital of Wenzhou Medical College.

Results: 16 cases were enrolled, followed by average age (36 +/- 11) years, mean duration after transplantation (4.3 +/- 2.1) months, mean course of disease (4.5 +/- 1.8) days. CT performance after admission revealed diffuse alveolar exudates and consolidation in all patients, and others still showed focal emphysema. With effective treatment, CT performance showed resolution of lung opacities completely until the second month, just little fiber remained. The pulmonary dysfunction showed apparent restrictive ventilatory abnormal and decreased DLco. Pulmonary dysfunction improved in the coming 3 - 4 weeks, and all dysfunction became complete resolution by the third month.

Conclusions: The characteristic CT performance was focused on the alveolar, with exudates, consolidation and focal emphysema. The main pulmonary dysfunction showed restrictive ventilatory abnormality and decreased DLco. Under effective therapy, these abnormalities would improve significantly by the third month.