Three cases of laryngopharyngeal primary squamous cell carcinoma presenting with thyroid nodules are described. The key message to take away from these cases is that patients with advanced malignancy of the upper aerodigestive tract can present with a thyroid nodule.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2270245 | PMC |
http://dx.doi.org/10.1258/jrsm.2008.070166 | DOI Listing |
Diagnostics (Basel)
December 2024
Department of Radiology and Diagnostic Imaging, University of Alberta Hospital, Edmonton, AB T6G2B7, Canada.
To determine the cancer risk in thyroid nodules using ACR TI-RADS. A retrospective analysis of all thyroid biopsies was performed over a 3-year period (2021 to 2023). Variables including gender, age, history of thyroid cancer or neck irradiation, nodule size and location, TR level, and sonographic features such as punctate echogenic foci (PEF), a very hypoechoic appearance, taller-than-wide shape, and suspected extrathyroidal extension were analyzed.
View Article and Find Full Text PDFCancers (Basel)
December 2024
Department of Otolaryngology Head and Neck Surgery, Sir Mortimer B. Davis-Jewish General Hospital, McGill University, Montreal, QC H3T 1E2, Canada.
Thyroid cancer is the most common endocrine malignancy, and accurate diagnosis is crucial for effective management. Fine needle aspiration cytology, guided by the Bethesda System for Reporting Thyroid Cytopathology, categorizes thyroid nodules into six categories, with Bethesda III and IV representing indeterminate diagnoses that pose significant challenges for clinical decision-making. Understanding the molecular profiles of these categories may enhance diagnostic accuracy and guide treatment strategies.
View Article and Find Full Text PDFCancers (Basel)
December 2024
IRIBHM Jacques E. Dumont, Université libre de Bruxelles, 1070 Brussels, Belgium.
Background: The diagnosis of malignant thyroid nodules is mainly based on the fine-needle aspiration biopsy (FNAB). To improve the detection of malignant nodules, different molecular tests have been developed. We present a new molecular signature based on altered miRNA expressions and specific mutations.
View Article and Find Full Text PDFCancers (Basel)
December 2024
Department of Nuclear Medicine, University of Münster and University Hospital Münster, 48149 Münster, Germany.
Thyroid nodules are common yet remain a diagnostic challenge. While ultrasound and Thyroid Imaging Reporting and Data Systems (TIRADS) are accepted as standard, the use of thyroid scintigraphy in euthyroid patients is debated. The European Association of Nuclear Medicine advocates it, whereas the American Thyroid Association and European Thyroid Association do not.
View Article and Find Full Text PDFJ Formos Med Assoc
January 2025
School of Medicine, Chung Shan Medical University, Taichung, Taiwan; Department of Surgery, Chung Shan Medical University Hospital, Taichung, Taiwan. Electronic address:
Background: Ethanol ablation (EA) has been proposed as a first-line treatment modality for recurrent symptomatic cystic thyroid nodules following initial aspiration. The efficacy of EA can be compromised when the initial nodule volume exceeds 10 mL. This study assessed the efficacy of single-session EA in managing thyroid cysts with an initial volume of ≥10 mL.
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