Sampling of radioiodine in air is accomplished by passing an air sample through an activated charcoal cassette. A mathematical model was developed, which assumes that radioiodine distribution along the cassette axis can be expressed by an exponential function. The model was validated experimentally for cassettes used for air sampling of radioiodine production boxes. There is a good agreement between the measurements and model predictions. Furthermore, when breakthrough occurs, the model can be used to estimate the activity that passed through the cassette unabsorbed.
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http://dx.doi.org/10.1016/j.apradiso.2008.02.043 | DOI Listing |
Environ Pollut
January 2025
State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China; Department of Head and Neck Surgery, Sun Yat-sen University Cancer Center, Guangzhou, China. Electronic address:
Differentiated thyroid cancer (DTC) generally has a favorable prognosis, and radioactive iodine (RAI) therapy is typically used for metastatic DTC that continues to progress and poses life-threatening risks. However, resistance to RAI in metastatic DTC significantly impairs treatment effectiveness. This study aims to identify potential compounds that may influence RAI efficacy.
View Article and Find Full Text PDFPhysiol Res
November 2024
The Fourth Department of Internal Medicine - Hematology, University Hospital Hradec Králové and Charles University, Faculty of Medicine in Hradec Králové, Hradec Králové, Czech Republic.
Appl Radiat Isot
October 2023
Department of Mechanical Engineering, Faculty of Engineering, Monoufiya University, Egypt.
Indoor Air Quality (IAQ) is very important topic in any radioisotope production facility. It is mandatory for some operators to be available behind hot cell that produce radioisotope to practice some tasks concerning maintenance, dosimetry and operation. One of these tasks is redundant transferring Radioiodine from cell to quality control lab and vice versa for measurements.
View Article and Find Full Text PDFFront Endocrinol (Lausanne)
October 2024
Division of Endocrinology and Metabolism, West China Hospital of Sichuan University, Chengdu, China.
Differentiated thyroid cancers (DTCs) constitute the primary histological subtype within thyroid cancer. Due to DTCs' distinctive radioiodine (RAI) uptake mechanism, standard treatment involving surgery, with or without adjunctive therapy using RAI and levothyroxine inhibition, typically yields favorable prognoses for the majority of patients with DTCs. However, this favorable outcome does not extend to individuals with decreased RAI uptake, termed radioiodine-refractory thyroid cancers (RAI-RTCs).
View Article and Find Full Text PDFInt J Mol Sci
October 2024
Department of Medicine and Oncology, Faculty of Medicine, Semmelweis University, 1083 Budapest, Hungary.
Thyroid cancer is the most common type of endocrine malignancy. Papillary thyroid carcinoma (PTC) is its predominant subtype, which is responsible for the vast majority of cases. It is true that PTC is a malignant tumor with a very good prognosis due to effective primary therapeutic approaches such as thyroidectomy and radioiodine (RAI) therapy.
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