We report four cases of double carcinoma of the esophagus and the lung. Case 1: a patient with synchronous double carcinoma of the esophagus and the lung underwent chemoradiotherapy (CRT) because of respiratory dysfunction. Case 2: a patient who was diagnosed with esophageal carcinoma after the surgery for lung carcinoma underwent CRT because of respiratory dysfunction. Case 3: a patient with synchronous double carcinoma underwent a two-stage operation. Case 4: a patient with synchronous double carcinoma underwent CRT at another hospital. To further treat the patients, we chose a two-stage operation. CRT is believed to be a feasible treatment in inoperable patients because patients 1 and 2 are alive 28 and 21 months after CRT, respectively. A two-stage operation is considered a suitably safe surgical procedure because no fatal postoperative complications occurred in cases 3 and 4.
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http://dx.doi.org/10.1007/s11748-007-0200-0 | DOI Listing |
Mol Cancer Ther
December 2024
National Center for Tumor Diseases, Heidelberg, Germany.
Ultra-high dose rate radiotherapy with electrons and protons has shown potential for cancer treatment by effectively targeting tumors while sparing healthy tissues (FLASH effect). This study aimed to investigate the potential FLASH sparing effect of ultra-high-dose rate helium ion irradiation, focusing on acute brain injury and subcutaneous tumor response in a preclinical in vivo setting. Raster-scanned helium ion beams were used to compare the effects of standard dose rate (SDR at 0.
View Article and Find Full Text PDFJ Cutan Pathol
December 2024
SkinPath Solutions, Smyrna, Georgia, USA.
Capicua transcriptional repressor (CIC)-rearranged sarcoma (CRS) is a rare and recently described tumor that most commonly affects patients between 15 and 30 years of age. It is an undifferentiated round cell malignancy, with a disease defining CIC fusion, with double homeobox 4 (DUX4) being the most common partner. Here, we report a 77-year-old woman who presented with a cutaneous thigh mass with a clinical morphology suggesting Merkel cell carcinoma.
View Article and Find Full Text PDFTurk J Med Sci
December 2024
Department of General Surgery, Faculty of Medicine, Giresun University, Giresun, Turkiye.
Background/aim: To investigate the association between the rs2267437, rs5751129 and rs132770 polymorphisms of the gene, which plays a role in repairing DNA double-strand breaks, and the risk of papillary thyroid carcinoma (PTC).
Materials And Methods: The study included 150 patients who had been diagnosed with PTC and 204 healthy controls. Genotyping of the SNPs was performed using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP).
Transl Oncol
December 2024
Department of General Surgery, Sanmen People's Hospital, Sanmen 317100, China. Electronic address:
Biosensors (Basel)
November 2024
State Key Laboratory of Chemical Safety, College of Control Science and Engineering, China University of Petroleum (East China), Qingdao 266580, China.
The detection and analysis of cancer cell exosomes with high sensitivity and precision are pivotal for the early diagnosis and treatment strategies of prostate cancer. To this end, a microfluidic chip, equipped with a cactus-like array substrate (CAS) based on surface-enhanced Raman spectroscopy (SERS) was designed and fabricated for the detection of exosome concentrations in Lymph Node Carcinoma of the Prostate (LNCaP). Double layers of polystyrene (PS) microspheres were self-assembled onto a polyethylene terephthalate (PET) film to form an ordered cactus-like nanoarray for detection and analysis.
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