Background And Purpose: Physical therapists frequently use the 66-item Gross Motor Function Measure (GMFM-66) with the Gross Motor Function Classification System (GMFCS) to examine gross motor function in children with cerebral palsy (CP). Until now, reference percentiles for this measure were not available. The aim of this study was to improve the clinical utility of this gross motor measure by developing cross-sectional reference percentiles for the GMFM-66 within levels of the GMFCS.
Subjects And Methods: A total of 1,940 motor measurements from 650 children with CP were used to develop percentiles. These observations were taken from a subsample, stratified by age and GMFCS, of those in a longitudinal cohort study reported in 2002. A standard LMS (skewness-median-coefficient of variation) method was used to develop cross-sectional reference percentiles.
Results: Reference curves were created for the GMFM-66 by age and GMFCS level, plotted at the 3rd, 5th, 10th, 25th, 50th, 75th, 90th, 95th, and 97th percentiles. The variability of change in children's percentiles over a 1-year interval also was investigated.
Discussion And Conclusion: The reference percentiles extend the clinical utility of the GMFM-66 and GMFCS by providing for appropriate normative interpretation of GMFM-66 scores within GMFCS levels. When interpreting change in percentiles over time, therapists must carefully consider the large variability in change that is typical among children with CP. The use of percentiles should be supplemented by interpretation of the raw scores to understand change in function as well as relative standing.
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http://dx.doi.org/10.2522/ptj.20070314 | DOI Listing |
Children (Basel)
January 2025
Child Health Department, Faculty of Medicine, Universitas Padjadjaran, Hasan Sadikin Hospital, Bandung 40161, West Java, Indonesia.
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View Article and Find Full Text PDFChildren (Basel)
December 2024
Faculty of Medicine, University Titu Maiorescu, 040441 Bucharest, Romania.
Our research aimed to assess if correlations could be found between items evaluated at the cerebral ultrasound performed at term-equivalent age (TEA) and neuro-motor outcomes evaluated at 12 and 24 months of corrected age in a group of preterm infants. The following were assessed: the Levine Index, the diagonals of the lateral ventricles, the size of the ventricular midbody, the sinocortical distance, the width of the basal ganglia, the cortical depth at the level of the cingular sulcus and the maturation of the gyral folding. The neurologic evaluation was performed at 12 and 24 months of corrected age, according to the Amiel Tison neurologic examination, and the items from the calendar of motor acquisitions were used as outcome measures of the study-gross and fine motor subsets.
View Article and Find Full Text PDFChildren (Basel)
December 2024
Department of Pediatrics, Division of Neonatology, University of Virginia, Charlottesville, VA 22908, USA.
Background/objectives: Motor deficits following neonatal brain injury, from cerebral palsy to subtle deficits in motor planning, are common yet underreported. Rodent models of motor deficits in neonatal hypoxia-ischemia (HI) allow improved understanding of the underlying mechanisms and neuroprotective strategies. Our goal was to test motor performance and learning in a mouse model of neonatal HI.
View Article and Find Full Text PDFBehav Sci (Basel)
January 2025
Institute of Human Movement and Sports Engineering, College of Physical Education and Health Sciences, Zhejiang Normal University, Jinhua 321004, China.
This study aimed to systematically review the measurement properties of the Test of Gross Motor Development-3 (TGMD-3) using the COSMIN methodology. A search of four databases (PubMed, EMBASE, Web of Science, CINAHL) identified 23 relevant studies. The methodological quality of the studies was assessed using the COSMIN risk of bias checklist; the measurement properties of the TGMD-3 were evaluated by the COSMIN quality criteria; and the quality of the evidence was rated using a modified GRADE approach.
View Article and Find Full Text PDFAnn Plast Surg
January 2025
Division of Plastic Surgery, Department of Surgery, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.
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Methods: A systematic review was conducted using PubMed/MEDLINE, Embase, and Cochrane on the 25th of March 2024.
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