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Pradofloxacin Minimum Inhibitory Concentration Profiling of Isolates: Insights into Antimicrobial Susceptibility in Swine.
Pathogens
January 2025
Elanco Animal Health, Greenfield, IN 46140, USA.
This study evaluated the minimum inhibitory concentration (MIC) of pradofloxacin against various swine respiratory pathogens, including , , , , and (), associated with disease in swine. This research was conducted in two phases: the initial phase examined isolates from the lungs that could be either commensal or pathogenic, while the second phase focused on systemic strains that spread from the respiratory tract to the brain. The pradofloxacin MIC values of the second phase were within the MIC range of the initial phase, with MIC and MIC values highlighting its potential as an effective antimicrobial agent.
View Article and Find Full Text PDF[Bacterial biofilm formation of peritoneal dialysis catheter in patients with peritonitis-associated catheter removal].
Beijing Da Xue Xue Bao Yi Xue Ban
February 2025
Department of Nephrology, Peking University People's Hospital, Beijing 100044, China.
Objective: Peritoneal dialysis(PD)-associated peritonitis is a common and major complication of PD and the most common cause of technical failure of PD. The presence of bacterial biofilm may be an important factor leading to refractory or recurrence of peritonitis. To investigate the formation and characteristics of bacterial biofilms on PD catheters after peritonitis-associated catheter removal.
View Article and Find Full Text PDFElectrochemiluminescence Resonance Energy Transfer Biosensor for the Human-Associated Clade of Based on Prereduction-Enhanced Yttrium MOFs.
Anal Chem
January 2025
National Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan 430070, China.
, a significant zoonotic pathogen, annually caused substantial economic losses in the swine industry and had intensified threat to public health due to the recent emergence of human-associated clade. In this study, we discovered that the rare-earth metal-based metal-organic frameworks (Y-BTC) possessed excellent ECL capabilities. After prereduction at high voltage, its ECL intensity was enhanced by two times.
View Article and Find Full Text PDFFunctional analysis of the type II toxin-antitoxin system ParDE in Streptococcus suis serotype 2.
BMC Vet Res
January 2025
College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, China.
Streptococcus suis (S. suis) is a major pathogen in swine and poses a potential zoonotic threat, which may cause serious diseases. Many toxin-antitoxin (TA) systems have been discovered in S.
View Article and Find Full Text PDFHuman infective endocarditis and septic shock caused by Streptococcus suis serotype 1.
BMC Infect Dis
January 2025
Wuming Hospital of Guangxi Medical University, Nanning, China.
Streptococcus suis(SS) infection is a zoonotic acute infectious disease, SS infective endocarditis is relatively rare, there is no case report of Streptococcus suis Serotype 1(SS1) causing mitral valve infection.The rapid progression of this patient's infection and the severe damage to the valve structure differ from the previous understanding of the relatively low virulence of SS1. Early diagnosis and selection of the correct antibiotic treatment according to the drug sensitivity is very important.
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