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The Application of Machine Learning Algorithms to Predict HIV Testing in Repeated Adult Population-Based Surveys in South Africa: Protocol for a Multiwave Cross-Sectional Analysis.

JMIR Res Protoc

January 2025

South African Medical Research Council/University of Johannesburg Pan African Centre for Epidemics Research Extramural Unit, Faculty of Health Sciences, University of Johannesburg, Johannesburg, South Africa.

Background: HIV testing is the cornerstone of HIV prevention and a pivotal step in realizing the Joint United Nations Program on HIV/AIDS (UNAIDS) goal of ending AIDS by 2030. Despite the availability of relevant survey data, there exists a research gap in using machine learning (ML) to analyze and predict HIV testing among adults in South Africa. Further investigation is needed to bridge this knowledge gap and inform evidence-based interventions to improve HIV testing.

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African, Caribbean, and Black (ACB) women are overrepresented among new HIV diagnoses due to social and structural factors. This study seeks to create, implement, and evaluate a community-based peer-led intervention to improve access to HIV prevention and care for ACB women in Canada. This multisite, five-year project, using community-based participatory research, implementation science and evaluation frameworks, will be implemented in five non-iterative phases.

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Epigenetic alteration in cervical cancer induced by human papillomavirus.

Int Rev Cell Mol Biol

January 2025

Posgrado en Ciencias Genómicas, Laboratorio de Patogenesis Celular y Molecular Humana y Veterinaria, Universidad Autónoma de la Ciudad de México, Ciudad de México, México. Electronic address:

The critical role of a subset of Human Papillomavirus in cervical cancer has been widely acknowledged and studied. Despite progress in our understanding of the viral molecular mechanisms of pathogenesis, knowledge of how infection with HPV oncogenic variants progresses from latent infection to incurable cancer has not been completely elucidated. In this paper we reviewed the relationship between HPV infection and epigenetic mechanisms such as histone acetylation and deacetylation, DNA methylation and non-coding RNAs associated with this infection and the carcinogenic process.

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Background: In Italy, the anti-Human Papillomavirus (HPV) vaccination campaign began in 2008. To date, despite the effectiveness and safety of HPV vaccines, coverage among Italian adolescents is still suboptimal. Evidence suggests that different factors could influence parents' choices regarding their children's vaccination uptake.

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Objectives: The aim of this research was investigating the role of lifestyle, knowledge and health beliefs in performing preventive behaviours against HPV in married women.

Background: Human Papilloma Virus (HPV) is a significant public health concern in Iran, with a relatively high prevalence in the general female population.

Methods: The study utilized a cross-sectional survey among 260 married women working at the university.

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