Board-certified neuropsychologists were surveyed and asked to assign a descriptive label (e.g., superior, average, normal, impaired) to 12 different standard scores (SS), from 50 to 130, of a memory test based on a brief case scenario. Surveys were returned by 49% (n = 110) of the target sample. The mean number of different classification labels assigned by participants to each of the 12 SS was 14 and ranged from 6 (for SS = 95) to 23 (for SS = 50). The mean percentages of participants who assigned the one or two most frequently used labels within each SS were 52.5% and 70.7%, respectively. Results revealed variable uniformity in assigning descriptive labels to specific standard scores, with significantly greater variability for SS in the lower half of the distribution and with applying impairment rather than normative labels. Professional and forensic implications are discussed.
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http://dx.doi.org/10.1080/13854040601064559 | DOI Listing |
Cardiovasc Pathol
January 2025
Department of Forensic Pathology, University Malaya Medical Centre, Lembah Pantai, 59100, WP Kuala Lumpur, Malaysia.
Aneurysmal Coronary Artery Disease (ACAD) can occur as localized dilations of a segment of one or more coronary arteries or diffuse ectasia-type dilatations of one or more coronaries. Atherosclerosis remains the most common cause of these aneurysms, with Kawasaki Disease being implicated in the Asian population. We present a case of a 62-year-old Asian woman who dies suddenly with no prior symptoms.
View Article and Find Full Text PDFInt Immunopharmacol
January 2025
Department of Molecular Pathology, The Affiliated Cancer Hospital of Zhengzhou University, Henan Cancer Hospital, Zhengzhou, Henan, China; Henan Key Laboratory of Molecular Pathology, Zhengzhou, Henan, China. Electronic address:
Background: Lung squamous cell carcinoma (LUSC) is a significant health concern, characterized by a lack of specific therapies and limited treatment options for patients in advanced stages. This study aims to identify key molecules of prognostic importance in LUSC and provide an experimental foundation for their potential therapeutic applications.
Methods: Immune-related transcriptome expression analysis was performed on LUSC samples using the NanoString digital gene analysis system to develop a prognostic transcriptomic signature.
Micron
December 2024
Graduate School of Natural and Applied Science, Biology Department, Bursa Uludağ University, Bursa, Turkey,; Arts and Sciences Faculty, Biology Department, Bursa Uludağ University, Bursa, Turkey. Electronic address:
Pollen grains, in addition to their allergenic properties, play an important role in the temporal and spatial analysis of forensic events and are considered secondary trace evidence. Pollen analysis requires expertise in microscopy techniques and palynology. This study aims to determine the persistence of pollen on common used fabric types and how much of it can be removed through washing.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.
Background: Genome-wide association studies (GWAS) in Alzheimer's disease (AD) leveraging endophenotypes beyond case/control diagnosis, such as brain amyloid β pathology, have shown promise in identifying novel variants and understanding their potential functional impact. In this study, we leverage two brain amyloid β pathology measurement modalities, PET imaging and neuropathology, to address sample size limitations and to discover novel genetic drivers of disease.
Method: We conducted a meta-analysis on an amyloid PET imaging GWAS (N = 7,036, 35% amyloid positive, 53.
Alzheimers Dement
December 2024
Department of Neurology, Mayo Clinic, Rochester, MN, USA.
Background: Limbic-predominant age-related TDP-43 encephalopathy (LATE) is a neuropathologically-defined disease, and it is frequently comorbid with Alzheimer's disease neuropathological change (ADNC). However, the neurological syndrome associated with LATE neuropathological change (LATE-NC) is not defined. We propose a set of clinical criteria for a limbic-predominant amnestic neurodegenerative syndrome (LANS) that is highly associated with LATE-NC.
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