Recently genetic variation in the DAPK1 and ABCA2 genes has been reported to be associated with late- and early-onset Alzheimer's disease (AD), respectively. We examined the most significant two single-nucleotide polymorphisms (SNPs) in DAPK1 in a large case-control cohort of late-onset subjects and matched controls and one of the most significant SNPs in ABCA2 in a small set of early-onset subjects as well. We did not detect associations with AD for any variation.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2763561 | PMC |
| http://dx.doi.org/10.1016/j.neurobiolaging.2008.01.006 | DOI Listing |
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