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Molar-incisor hypomineralization (MIH) is a qualitative enamel alteration that asymmetrically affects the first molars and may also affect permanent incisors, clinically presenting as demarcated opacities with white, yellow, or brown discoloration. This condition can lead to increased risk of caries, esthetic impairment, fractures, and tooth loss. The aim of this case report is to describe the implementation of an esthetic treatment involving dental bleaching, resin infiltration (RI), and composite resin restoration for a patient with MIH.
View Article and Find Full Text PDFAssessing the marginal seal of bioactive restorative materials in class II cavities with a bacterial penetration model.
Dent Mater
March 2025
Department of Conservative Dentistry and Periodontology, LMU University Hospital, LMU Munich, Goethestrasse 70, Munich 80336, Germany.
Objectives: The aim of this study was to examine the marginal seal of novel bioactive restorative materials and the material-related properties associated with bacterial microleakage.
Methods: Class II cavities prepared into human extracted teeth were restored with: Venus Diamond (VD) + selective enamel etching (SEE)/self-etching universal adhesive (SEA), ACTIVA BioACTIVE RESTORATIVE (AB) + SEE/SEA, Cention Forte (CF) + Cention Primer, Ketac Universal Aplicap (KU), EQUIA Forte HT (EF) and Surefil One (SO) and exposed to a cariogenic multi-species bacterial suspension for 7 days. Bacterial microleakage was visualized with a modified gram staining protocol and bacterial penetration depths were microscopically determined after sectioning the teeth.
Comparative Analysis of the Clinical Performance of Three Different Inlays Based on Fabrication: An Study.
J Pharm Bioallied Sci
December 2024
Conservative Dentistry and Endodontics, Rajas Dental College and Hospital, Tirunelveli, Tamil Nadu, India.
Context: Novelty in today's dental practice aims at superiority in aesthetics. Dental practitioners address patient anxiety about retaining teeth while maintaining aesthetic appeal. The debate revolves around the best approach to meet their aesthetic and functional needs, leading to the development of various inlay techniques.
View Article and Find Full Text PDFBiosynthesis of titanium dioxide nanoparticles using Sargassum tenerrimum as reductant and deciphering its antibiofilm role against cariogenic Candida albicans.
Microb Pathog
May 2025
Department of Prosthodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai, Tamil Nadu, India; Centre for Marine and Aquatic Research, Saveetha Medical College, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai, Tamil Nadu, India. Electronic address:
The present study aimed to biosynthesize titanium dioxide nanoparticles (TiONPs) using marine macroalgae Sargassum tenerrimum (ST) and ascertain its ability to impede biofilm formation, exopolysaccharide production and induce protein leakage in dental caries-forming Candida albicans. Characterization of ST-TiONPs by UV-Vis spectra recorded a sharp peak at 365 nm. FT-IR results showed active functional groups involved in stabilizing the ST-TiONPs.
View Article and Find Full Text PDFArtemisinin regulates cell proliferation, apoptosis, and the inflammatory response of human dental pulp stem cells through the p53 signaling pathway under LPS-induced inflammation.
Int Immunopharmacol
March 2025
Department of Prosthodontic Technology, Nanjing Stomatological Hospital, Affiliated Hospital of Medical School, Institute of Stomatology, Nanjing University, Nanjing, Jiangsu 210008, PR China. Electronic address:
Objective: The purpose of this study was to investigate the effects and mechanism of artemisinin (ART) on the proliferation, apoptosis, and inflammatory response of human dental pulp stem cells (HDPSCs) under lipopolysaccharide (LPS)-induced inflammation.
Methods: HDPSCs were isolated, cultured, and identified by flow cytometry and three-directional differentiation induction. A suitable concentration of LPS was selected to mimic the inflammatory condition in vitro.
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