A new polyphenol, designated as salvianolic acid N, was isolated from the aqueous extracts of the roots of Salvia yunnanensis. Its chemical structure was elucidated as 3-(3,4-dihydroxylphenyl)-2-[(E)-3-(1,8,9-trihydroxyl-dibenzo[b,f]oxpin-3-yl)acryloxloxy]propanoic acid (1) on the basis of NMR and MS spectral analyses. The new polyphenol inhibited both HIV-1 IN in vitro and also reduced HIV-1 p24 antigen in MT-4 cell lines.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1080/10286020701605075 | DOI Listing |
Publication Analysis
Top Keywords
salvia yunnanensis
8
potent anti-hiv
4
anti-hiv polyphenol
4
polyphenol salvia
4
yunnanensis polyphenol
4
polyphenol designated
4
designated salvianolic
4
salvianolic acid
4
acid isolated
4
isolated aqueous
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!