Off-label prescription of approved drugs is common and often necessary in pediatric practice. Off-label prescription of approved drugs does not constitute malpractice and is not considered experimental therapy. Pediatric providers should endeavor to become familiar with commonly prescribed off-label drugs and strive to limit their prescribing to the drugs with existing pediatric experience. Pediatric providers may choose to inform parents that a drug is being used in an off-label manner, but informed consent is not required.
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