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The association between metabolic dysfunction-associated steatotic liver disease diagnosis and vasomotor symptoms in midlife women.
Menopause
December 2024
Division of Community Internal Medicine, Department of Medicine, Mayo Clinic, Jacksonville, FL.
Objective: Metabolic dysfunction-associated steatotic liver disease (MASLD) and vasomotor symptoms (VMS) are associated with increased cardiovascular disease risk. Although visceral adiposity has been linked to MASLD and VMS independently, this study aimed to evaluate associations between the two in midlife women.
Methods: A cross-sectional study of women aged 45-60 years receiving primary care at one of four sites was conducted from March 1 through June 30, 2021.
Emergency Care Use During Pregnancy and Severe Maternal Morbidity.
JAMA Netw Open
October 2024
Cityblock Health, Brooklyn, New York.
Importance: Pregnant individuals who repeatedly use emergency care during pregnancy represent a population who could be disproportionately vulnerable to harm, including severe maternal morbidity (SMM).
Objective: To explore patterns of unscheduled care visits during pregnancy and ascertain its association with SMM at the time of birth.
Design, Setting, And Participants: This cohort study used data from a statewide database that linked hospital records to births and fetal deaths occurring between October 1, 2002, and March 31, 2020, in Massachusetts.
Risk of Invasive Fungal Infections in Patients With Chronic Lymphocytic Leukemia Treated With Bruton Tyrosine Kinase Inhibitors: A Case-Control Propensity Score-Matched Analysis.
Open Forum Infect Dis
June 2024
Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
Background: Prior reports have suggested a possible increase in the frequency of invasive fungal infections (IFIs) with use of a Bruton tyrosine kinase inhibitor (BTKi) for treatment of chronic lymphoid malignancies such as chronic lymphocytic leukemia (CLL), but precise estimates are lacking. We aim to characterize the prevalence of IFIs among patients with CLL, for whom a BTKi is now the first-line recommended therapy.
Methods: We queried TriNetX, a global research network database, to identify adult patients with CLL using the code (C91.
Investigating the association between metabolic syndrome conditions and perinatal mental illness: a national administrative claims study.
BMC Pregnancy Childbirth
June 2024
Division of Management Policy and Community Health, Center for Healthcare Data Research, The University of Texas Health Science Center at Houston School of Public Health, Houston, TX, USA.
Background: Although the association between mental disorder and metabolic syndrome as a bidirectional relationship has been demonstrated, there is little knowledge of the cumulative and individual effect of these conditions on peripartum mental health. This study aims to investigate the association between metabolic syndrome conditions (MetS-C) and maternal mental illness in the perinatal period, while exploring time to incident mental disorder diagnosis in postpartum women.
Methods: This observational study identified perinatal women continuously enrolled 1 year prior to and 1 year post-delivery using Optum's de-identified Clinformatics® Data Mart Database (CDM) from 2014 to 2019 with MetS-C i.
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