Aim: To analyse echinococcosis morbidity and course characteristics in men serving in the Navy.
Material And Methods: The results of annual 1983-2006 check-up of Navy men were analysed to estimate echinococcosis morbidity in patients with eosinophilia and tumors including cysts. The diagnosis was made with application of clinical, ultrasound, radionuclide, morphological (including parasitological), biochemical and immunological methods, computed tomography.
Results: 14 cases of hydatid echinococcosis were documented. Most of the patients (85.7%) were young (18-22 years of age). The patients were infected before the army in highly endemic regions. Solitary echinococcosis was detected in 8 patients. In multiple echinococcosis 1 patient had 4 cysts, 3 patients--3, 2 patients had 2 cysts. Echinococcosis of stage 1 was diagnosed in 3 patients, stage 2--in 11 patients. All the patients had cysts in the liver. In multiple echinococcosis the cysts occurred more often in the liver, spleen, kidney; they were rare in the lungs, bones, brain. Pain, asthenovegetative, dyspeptic and allergic syndromes were registered in 71.4, 28.6, 14.3 and 7.1 cases, respectively. Eosinophilia was encountered in 42.9% cases. These syndromes were, as a rule, weakly pronounced. Before accurate diagnosis 6 patients for 4-10 months were treated outpatiently for chronic gastroduodenitis, recurrent lumbalgia, biliary dyskinesia and intercostal neuralgia.
Conclusion: Echinococcosis incidence rate in the Navy men is very low. They are infected before the army. The disease is diagnosed by chance or late, manifests primarily with pain symptoms.
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J Gastrointest Surg
January 2025
Department of Surgery, The Ohio State University Wexner Medical Center, Columbus, OH.
Introduction: Cystic echinococcosis is a widely endemic helminthic disease caused by infection with metacestodes (larval stage) of the Echinococcus granulosus tapeworm, which is transmitted by dogs and found on every continent except Antarctica. We sought to review the life cycle, epidemiology, symptoms, diagnostic methods, and treatment of Echinococcus granulosus of the liver.
Methods: A comprehensive review was conducted using Medline/PubMed, Google Scholar, Cochrane Library, and the Web of Science accessed between 1990 and 2024.
Clin Microbiol Infect
January 2025
University of Zagreb, School of Medicine, Zagreb, Croatia; University Hospital for Infectious Diseases "Dr. Fran Mihaljević", Zagreb, Croatia. Electronic address:
Int J Surg Case Rep
January 2025
Department of Pathology and Laboratory Medicine, Jigme Dorji Wangchuck National Referral Hospital, Thimphu, Bhutan.
Introduction: Echinococcus is a common infection in an endemic country like Bhutan. Mediastinal echinococcosis is rare. Although presentation due to a mediastinal echinococcal cyst is variable according to the cyst's location, a reaction due to rupture of the cyst and simultaneous reaction to an administration of antibiotics such as ceftriaxone can cause a diagnostic challenge.
View Article and Find Full Text PDFActa Trop
January 2025
Department of Department of Anesthesiology, the First Affiliated Hospital of Xinjiang Medical University, No. 137, South Liyushan Road, Xinshi District, Urumqi, Xinjiang, 830054, China; Xinjiang Perioperative Organ Protection Laboratory, No. 137, South Liyushan Road, Xinshi District, Urumqi, Xinjiang, 830054, China. Electronic address:
Echinococcosis, a zoonotic disease, significantly impacts the liver, with alveolar echinococcosis (AE) often leading to liver fibrosis and, in severe cases, cirrhosis. However, the molecular mechanisms by which AE infection promotes liver fibrosis remain incompletely understood. This study utilized bioinformatic analysis of existing microarray data to explore the shared mechanisms between AE and liver fibrosis and to identify potential therapeutic drug candidates.
View Article and Find Full Text PDFViruses
December 2024
School of Veterinary Medicine, Xinjiang Agricultural University, Urumqi 830052, China.
Canids act as a crucial intermediary in the transmission of rabies and , serving as co-infection hosts and pathogen carriers for both rabies and hydatid disease (HD) transmitted from animals to humans. Therefore, an effective and efficient bivalent oral vaccine for preventing HD and rabies is urgently required to reduce economic losses in husbandry resulting from rabies and HD. In this study, a full-length plasmid (pcDNA4-NPM+G+EgM123+eGFP+L) carrying the gene and fluorescence reporter genes of eGFP and four auxiliary transfection plasmids of rabies virus SRV (pcDNA4-N, pcDNA4-P, pcDNA4-G, pcDNA-L) were established by reverse genetics approaches and co-transfected to BSR cells by electrotransfection.
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