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Alkaptonuria presenting as lumbar degenerative disease: A case report and literature review.
Medicine (Baltimore)
January 2025
Ningbo Medical Center LiHuiLi Hospital, Ningbo, Zhejiang, PR China.
Rationale: Alkaptonuria (AKU) is a rare, inherited metabolic disease caused by deficient activity of homogentisic acid oxidase, leading to the accumulation of homogentisic acid and its oxidized product, benzoquinone acetic acid. These compounds cause black discoloration of cartilage, degeneration, inflammation, and calcification of intervertebral disks and large joints, resulting in pain and impaired quality of life. Despite its debilitating effects, there are no curative treatments for AKU, and management remains supportive.
View Article and Find Full Text PDFAn Acta Orthopaedica educational article: Treatment of pediatric spondylolysis and spondylolisthesis.
Acta Orthop
January 2025
Helsinki New Children's Hospital, Helsinki University Hospital, Helsinki, Finland.
Spondylolysis is defined as a defect or elongation in the pars interarticularis of the lumbar spine, either unilateral or bilateral. Growing children with bilateral spondylolysis may develop spondylolisthesis, i.e.
View Article and Find Full Text PDFProspective study on a new combination of pulsed radiofrequency and platelet-rich plasma injections for managing grade I lumbosacral spondylolisthesis.
Sci Rep
January 2025
Faculty of Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, 700000, Vietnam.
Our study aimed to investigate the clinical benefits of combining pulsed radiofrequency (PRF) and platelet-rich plasma (PRP) techniques for treating chronic lumbosacral radicular (CLSR) pain resulting from grade I spondylolisthesis (G1SL). Ninety-six patients with CLSR pain between March 2021 and March 2023 were included in this study, 58 patients with G1SL without instability on dynamic radiographs - Group A and 38 patients with instability - Group B. Pre-procedure, Group B had higher pain levels than Group A.
View Article and Find Full Text PDF[O-arm Versus C-arm: Comparison of the Learning Curves and Accuracy in Transpedicular Screw Fixation of Lumbar Spondylolisthesis].
Acta Chir Orthop Traumatol Cech
January 2025
Neurochirurgická klinika Fakultní nemocnice Olomouc.
Purpose Of The Study: The annual number of spinal fusion procedures has been increasing and is well documented worldwide. The O-arm is slowly becoming the standard for transpedicular screw insertion. The accuracy and safety of this method have been confirmed by many studies.
View Article and Find Full Text PDFSurgeon Recommendation and Outcomes of Decompression With vs Without Fusion in Patients With Degenerative Spondylolisthesis.
JAMA Netw Open
January 2025
Kysthospitalet in Hagevik, Orthopedic Department, Haukeland University Hospital, Bergen, Norway.
Importance: The ability of surgeons to choose the right patient for fusion in addition to decompression when operating for degenerative spondylolisthesis with symptomatic spinal stenosis is debated. The addition of fusion increases risk, morbidity, and costs but has been claimed to give better results for selected patients.
Objective: To investigate whether following surgeons' opinions regarding fusion was associated with clinical outcomes.
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