Severity: Warning
Message: file_get_contents(https://...@pubfacts.com&api_key=b8daa3ad693db53b1410957c26c9a51b4908&a=1): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
Filename: helpers/my_audit_helper.php
Line Number: 176
Backtrace:
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 176
Function: file_get_contents
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 250
Function: simplexml_load_file_from_url
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 3122
Function: getPubMedXML
File: /var/www/html/application/controllers/Detail.php
Line: 575
Function: pubMedSearch_Global
File: /var/www/html/application/controllers/Detail.php
Line: 489
Function: pubMedGetRelatedKeyword
File: /var/www/html/index.php
Line: 316
Function: require_once
Among wide assortment of pharmaceutical remedies, that use modern medicine as a weapon against different diseases, special place belongs to the ophthalmic pharmaceutical forms, and their development presents independent branch of pharmaceutical technology. Recently, as a reason of various diseases and among them ophthalmic problems, is considered free radicals and reactions with their participation. Protection of the organism from such diseases presents a main goal of antioxidant system. Nowadays, special attention is paid to the natural antioxidants. On the basis of the natural honey technology of eye drops davikol with antioxidant activity have been developed. The objective of our study has been the development of the substance of prolonged pharmaceutical dosage form davikol - eye ophthalmic drops and its standardization. The qualitative and quantitative methods were developed. It is concluded that the optimal method of drying of davikol is sublimation. Dry powder (active substance) davikol was obtained; quality characteristics were identified.
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