Heterotopic gastric mucosa (HGM) can be found throughout the entire gastrointestinal tract, more frequently in the cervical oesophagus. Macroscopic HGM is named inlet patch (IP). The great majority of IPs are asymptomatic and discovered incidently during oesophageal endoscopy performed for another pathology. However, complications can occur. Among these, perforation is extremely rare. We report a case of a 27-year old man who presented with a perforation of an upper oesophageal ulcer arising from an IP. The diagnosis was made during endoscopy and confirmed with biopsy of the tissue surrounding the perforation, showing histologic modifications consistent with heterotopic gastric mucosa. Medical treatment using a proton pump inhibitor and antibiotics delivered with a gastric tube was advocated. The perforation was closed at day 7 and plasma Argon coagulation of the inlet patch was performed two months later. Annual endoscopy has been normal for three years.
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Gastroenterol Res Pract
January 2025
Department of Gastroenterology, Tongji Institute of Digestive Diseases, Tongji Hospital, School of Medicine, Tongji University, Shanghai, China.
This study is aimed at comparing the clinical characteristics and histological types of symptomatic and asymptomatic patients with heterotopic gastric mucosa in the upper esophagus (HGMUE) and exploring the factors influencing the occurrence and severity of laryngopharyngeal reflux (LPR) symptoms in these patients. HGMUE is a potential cause of LPR symptoms. This retrospective analysis evaluated 70 patients with HGMUE using a detailed questionnaire.
View Article and Find Full Text PDFVirchows Arch
November 2024
Department of Pathology and Immunology, Washington University in St. Louis, 660 South Euclid Avenue, Campus, Box 8118, St. Louis, MO, 63110, USA.
Cureus
October 2024
Pathology, The University of Alabama at Birmingham, Birmingham, USA.
Heterotopia or ectopic tissue refers to the presence of normal tissue in an abnormal location, away from its typical anatomic site. While heterotopia is not uncommon, its occurrence in the gallbladder is quite rare, and even more unusual is the presence of gastric heterotopia within the gallbladder. This case report describes a 41-year-old female patient with oxyntic-type heterotopic gastric mucosa in the proximal body of the gallbladder.
View Article and Find Full Text PDFInt J Surg Pathol
November 2024
Department of General Surgery, Hacettepe University Faculty of Medicine, Ankara, Turkey.
Pancreatic heterotopia is the presence of pancreatic tissue in a different anatomical location with no connection to the main pancreas. The most common locations in the gastrointestinal system are duodenum, stomach, and Meckel diverticulum. However, it is quite rare in the hepatobiliary system.
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