Synthesis of 1-{4-[4-(adamant-1-yl)phenoxymethyl]-2-(4-bromophenyl)- 1,3-dioxolan-2-ylmethyl}imidazole with expected antifungal and antibacterial activity.

Acta Pol Pharm

Department of Organic Chemistry, Faculty of Pharmacy, Medical University of Warsaw, 1 Banacha Str., 02-097 Warsaw, Poland.

Published: April 2008

A multistep synthesis of a new analogue of ketoconazole, which was expected to show antifungal and antibacterial activity, has been described.

Download full-text PDF	Source

Publication Analysis

expected antifungal

antifungal antibacterial

antibacterial activity

synthesis 1-{4-[4-adamant-1-ylphenoxymethyl]-2-4-bromophenyl-

1-{4-[4-adamant-1-ylphenoxymethyl]-2-4-bromophenyl- 13-dioxolan-2-ylmethyl}imidazole

13-dioxolan-2-ylmethyl}imidazole expected

activity multistep

multistep synthesis

synthesis analogue

analogue ketoconazole

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!