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| http://dx.doi.org/10.5688/aj720111 | DOI Listing |
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Protocol for the development of a guideline on post-extubation respiratory support for mechanically ventilated patients in the ICU.
BMJ Open
January 2025
Evidence based medicine center, Lanzhou University, Lanzhou, Gansu, China.
Unlabelled: Prophylactic respiratory support for patients after extubation is effective in improving their outcomes and prognosis. However, the optimal post-extubation respiratory support for different populations and disease types of mechanically ventilated patients remains controversial, and there is a lack of detailed, multidisciplinary, evidence-based recommendations for clinical application.
Methods And Analysis: This protocol strictly follows the development process outlined in the WHO Handbook for Guideline Development and Guidelines 2.
Essential resources and best practices for laboratory mouse research.
Mol Cells
January 2025
Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon, South Korea, 34141. Electronic address:
The laboratory mouse (Mus musculus) is the most widely used mammalian model organism in biomedical and life science research. This concise guide aims to provide essential information to assist researchers new to working with mice, covering topics such as mouse husbandry, maintenance, and available resources for obtaining mouse strains and associated data. Additionally, we discuss ethical considerations, emphasizing the 3Rs (replacement, reduction, and refinement) to ensure responsible and humane research practices.
View Article and Find Full Text PDFEvaluation of color in digital nuclear power plant control room displays.
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January 2025
Idaho National Laboratory, 1955 Fremont Avenue, Idaho Falls, ID, 83415, United States.
Human system interface design in industrial process control is guided by industry standards, human factors best practices, and domain-specific conventions, and often there is a conflict between one or more of the sources of design input for specific design elements. In the nuclear domain, one design element for which conflict arises is the use of color to represent equipment state. This study evaluates the tradeoffs associated with using color in a process control display versus using white and shades of gray.
View Article and Find Full Text PDFEight quick tips for biologically and medically informed machine learning.
PLoS Comput Biol
January 2025
Dipartimento di Informatica Sistemistica e Comunicazione, Università di Milano-Bicocca, Milan, Italy.
Machine learning has become a powerful tool for computational analysis in the biomedical sciences, with its effectiveness significantly enhanced by integrating domain-specific knowledge. This integration has give rise to informed machine learning, in contrast to studies that lack domain knowledge and treat all variables equally (uninformed machine learning). While the application of informed machine learning to bioinformatics and health informatics datasets has become more seamless, the likelihood of errors has also increased.
View Article and Find Full Text PDFCreating custom GPTs for faculty development: An example using the Johari Window and Crucial Conversation frameworks for providing feedback to struggling students.
Med Teach
January 2025
Professor of Medicine and Executive Dean, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University School of Medicine, Cleveland, OH, USA.
Feedback plays a crucial role in the growth and development of trainees, particularly when addressing areas needing improvement. However, faculty members often struggle to deliver constructive feedback, particularly when discussing underperformance. A key obstacle is the lack of comfort many faculty experience in providing feedback that fosters growth.
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