Sentinel mouse seroconversion to infectious agents is critical for laboratory animal facility disease monitoring. We report spontaneous emergence of non-sex-linked agammaglobulinemia with B-cell deficiency and cutaneous Staphylococcus aureus granulomatosis (botryomycosis) in a cohort of related Swiss Webster sentinel mice. Our experience reinforces the importance of immunocompetency validation in surveillance programs.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2395093 | PMC |
| http://dx.doi.org/10.1128/JCM.01875-07 | DOI Listing |
Publication Analysis
Top Keywords
staphylococcus aureus
8
botryomycosis cohort
8
swiss webster
8
agammaglobulinemia staphylococcus
4
aureus botryomycosis
4
cohort sentinel
4
sentinel swiss
4
webster mice
4
mice sentinel
4
sentinel mouse
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!