The postural reactions of 10 moderate PD patients and 10 age matched controls were studied during stance on a sinusoidally back and forth moving platform during 5 blocks of 10, 1-min trials. Free stance was followed by weight bearing, lowering or raising the center of gravity (COG) by 10%. Next, a book was balanced on the head and finally, forward inclination was constrained. Normal stance strategy, including predictive muscle responses was found during free stance. Modifying COG height caused little response changes. Stance strategy became abnormal when head trajectory or forward inclination was restricted, indicating that ability to generate a nonstandard multi-joint stance strategy, rather than production of adequate stabilizing forces, is impaired in moderate, medicated PD patients.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.parkreldis.2007.12.002 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
#Opioids: A Mixed Methods Examination of Top Opioid-Related Content on TikTok.
J Stud Alcohol Drugs
December 2024
Center for Alcohol and Addiction Studies, Brown University School of Public Health, Providence, RI.
Objective: Despite an abundance of public discourse about the opioid crisis in the media, there is little research characterizing opioid-related content on TikTok, a popular video-based social media platform. This study sought to examine how opioids are portrayed on TikTok.
Methods: This study used mixed-methods to analyze top opioid-related posts marked with the hashtag "#opioids" collected in May 2023.
"Busting the hidden curriculum" a realist and innovative perspective to foster professional behaviors.
Front Med (Lausanne)
December 2024
Centre for Professionalism in Medicine and Health Sciences, Faculty of Medicine and Health Sciences, RCSI University of Medicine and Health Sciences, Dublin, Ireland.
Contemporary health professions education has long delineated the desired attributes of medical professionalism in the form of standard curricula and their role in forming professional behaviors (PBs) among aspiring doctors. However, existing research has shown the contradictory and powerful role of hidden curriculum (HC) in negatively influencing medical students' PBs through unspoken or implicit academic, cultural, or social standards and practices. These contrasting messages of formal curricula and HC lead to discordance and incongruence in future healthcare professionals developing professional identity formation.
View Article and Find Full Text PDFFatigue-induced modifications to trunk and lower-limb coordination mode during drop vertical jump and sidestep cutting tasks in female handball athletes.
Gait Posture
December 2024
Laboratory of Technology and Sport Performance, School of Physical Education and Sport, University of São Paulo, São Paulo, Brazil. Electronic address:
Background: Examining movement patterns in athletic activities is crucial for understanding the mechanisms and contributing factors linked to lower limb injuries, with the knee joint being particularly vulnerable in team sports like handball.
Research Question: How does a handball-specific fatigue protocol affect trunk-knee and hip-knee intersegmental coordination during the drop vertical jump (DVJ) and sidestep cutting maneuver (SCM) in handball players?
Methods: Twenty female handball athletes participated, performing three trials of each task before and after undergoing the fatigue protocol. Using a motion capture system, the trunk, hip, and knee joint angles were recorded in all three planes and time-normalized to 100 % of the stance phase.
Uncertainty Management in Chinese Mainstream Media's Health Communication on Weibo After COVID-19 Policy Shifts: A Discursive Exploration.
Health Commun
December 2024
School of Foreign Languages, Jiangsu University of Science and Technology.
Given the influence of emotional management on social media in public health communication, examining the discursive strategies employed in health-crisis communication is crucial. Using the Weibo posts of the as a data source, this study analyzes the discursive strategies and resources employed by the mainstream media to address uncertainties pertaining to a 2022 shift in COVID-19 policy. The findings reveal that the mainstream media use both informational and emotional strategies, expressing various epistemic stances and promoting positivity while countering negativity.
View Article and Find Full Text PDFChallenging the Standard Immunogenicity Assessment Approach: 1-Tiered ADA Testing Strategy in Clinical Trials.
AAPS J
December 2024
Regeneron Pharmaceuticals, Bioanalytical Sciences, 777 Old Saw Mill River Road, Tarrytown, New York, 10591, USA.
The ADA testing strategy for protein therapeutics was established almost two decades ago when assay methodologies were rudimentary, and serious immunogenicity-related safety issues had recently been observed with some biotherapeutics. The current testing paradigm employs multiple tiers and stringent cut points to minimize false negatives, reflecting a conservative stance towards ADA analysis. The development of highly sensitive ADA assay platforms and technologies such as humanized or fully human monoclonal antibody (mAb) drugs has put the traditional, resource-intensive 3-tiered testing approach under scrutiny.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!