[Sigmoid carcinoma as a long-term complication following ureterosigmoidostomy].

Ned Tijdschr Geneeskd

St. Antonius Ziekenhuis, Postbus 2500, 3430 EM Nieuwegein.

Published: January 2008

A 45-year-old woman, known to have a congenital exstrophy ofthe bladder, for which she underwent a ureterosigmoidostomy in her infancy, presented with fever. This was due to pyelonephritis, from which she recovered with antibiotic therapy. During colonoscopy a carcinoma of the sigmoid was found at the level of the anastomosis of the ureters. Patients with a ureterosigmoidostomy have a one hundred-fold increased risk of colon carcinoma compared to the general population. The development of malignant tumours as a long-term complication of this procedure is linked with the frequent contact between intestinal tissue and urine. Periodical colonoscopy of these patients is advised.

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