The mechanisms by which supervised physical training improves walking ability in patients with intermittent claudication (IC) are microcirculatory, rheological, and metabolic. The main mechanism of levo-propionylcarnitine (LPC) is metabolic; it increases the walking ability in claudicants, providing an additional energy to the ischemic muscle by an anaplerotic activity. Therefore, the current study was carried out to ascertain whether the combined treatment has a synergistic effect. The results confirm the effectiveness of supervised physical training in patients with IC, and we recommend the use of LPC during the exercise training program, at least in patients with severe claudication. Finally, underlining the similar mechanisms of physical training and LPC treatment, the study suggests that a cycle of LPC infusions could be advised in patients with severe claudication who cannot be included, for various reasons, in an exercise rehabilitation program.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1177/0003319707304567 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Exploring geriatric syndromes among physically disabled older adults: A network analysis.
Geriatr Nurs
January 2025
School of Nursing, Fudan University, Shanghai 200032, China. Electronic address:
Objective: To explore the network structure of common geriatric syndromes and conditions in physically disabled older adults.
Methods: We chose fourteen common geriatric syndromes and conditions from the dataset and estimated networks with the partial correlation network method. We tested the stability and accuracy of the network using the package "bootnet" in R software.
Stress, resilience and sense of self-efficacy among Ukrainian, Polish, Romanian, and Slovak women during the Russian invasion of Ukraine.
Psychiatr Pol
October 2024
Uniwersytet Pomorski w Słupsku.
Objectives: The aim of the current study was to determine the levels of stress, resilience and the sense of self-efficacy, as well as the influence of resilience and the sense of self-efficacy in shaping stress levels, in a sample of women from various countries of origin.
Methods: The study was carried out on a sample of Ukrainian (N = 82), Polish (N = 102), Slovak (N = 79), and Romanian (N = 42) women using the Sense of Stress Questionnaire, the General Self-Efficacy Scale and the Brief Resilience Scale.
Results: Highest total stress levels were found among Ukrainian women, while the lowest were found among Polish women.
Adhesion-driven vesicle translocation through membrane-covered pores.
Biophys J
January 2025
Theoretical Physics of Living Matter, Institute of Biological Information Processing and Institute for Advanced Simulation, Forschungszentrum Jülich, 52425 Jülich, Germany. Electronic address:
Translocation across barriers and through constrictions is a mechanism that is often used in vivo for transporting material between compartments. A specific example is apicomplexan parasites invading host cells through the tight junction that acts as a pore, and a similar barrier crossing is involved in drug delivery using lipid vesicles penetrating intact skin. Here, we use triangulated membranes and energy minimization to study the translocation of vesicles through pores with fixed radii.
View Article and Find Full Text PDFA participatory needs assessment to map the system dynamics of overweight related behaviours of 10-14-year-old adolescents living in an underserved neighbourhood in Amsterdam, the Netherlands.
BMC Public Health
January 2025
Amsterdam UMC location Vrije Universiteit Amsterdam, Public and Occupational Health, De Boelelaan 1117, Amsterdam, the Netherlands.
Background: Developing interventions along with the population of interest using systems thinking is a promising method to address the underlying system dynamics of overweight. The purpose of this study is twofold: to gain insight into the perspectives of adolescents regarding: (1) the system dynamics of energy balance-related behaviours (EBRBs) (physical activity, screen use, sleep behaviour and dietary behaviour); and (2) underlying mechanisms and overarching drivers of unhealthy EBRBs.
Methods: We conducted Participatory Action Research (PAR) to map the system dynamics of EBRBs together with adolescents aged 10-14 years old living in a lower socioeconomic, ethnically diverse neighbourhood in Amsterdam East, the Netherlands.
Effects of a 16-week dance intervention on loneliness and self-esteem in left behind children: a randomised controlled trial.
Sci Rep
January 2025
Department of Human Movement Science, Hunan Normal University, 36 Lushan Road, Changsha, Hunan, China.
Loneliness and low self-esteem are among the more prominent mental health problems among left-behind children, but most of the current research stays in cross-sectional surveys, with fewer studies proposing specific solutions. In addition, although the effective impact of dance interventions on loneliness and self-esteem has been demonstrated, the impact in the group of left-behind children remains under-explored. Therefore, this study validated the effectiveness of a dance intervention on loneliness and self-esteem in left-behind children through a 16-week randomised controlled trial.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!