Myocardial dysfunction in chagasic patients with no apparent heart disease.

Arq Bras Cardiol

Departamento de Clínica Médica, Programa de Pós-Graduação em Medicina Tropical, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brasil.

Published: December 2007

Background: The Tei index simultaneously evaluates the ventricular systolic and diastolic functions. It has a good correlation with hemodynamic data and has enabled the detection of initial ventricular function alterations of different etiologies.

Objective: To study initial biventricular function alterations in chagasic patients with no apparent heart disease, using the Tei index.

Methods: Forty eight individuals were evaluated. Group 1 was comprised of 25 patients diagnosed with Chagas' disease with no apparent heart disease and normal echocardiogram; group 2 was comprised of 23 healthy individuals with negative serological tests for Chagas' disease.

Results: The Tei index was significantly higher in the group of chagasic patients with no apparent heart disease when compared to that of the control group: left ventricular Tei index (0.48 +/-0.11 vs. 0.36 +/- 0.06, p < 0.001) , right ventricular Tei index (0.34 +/- 0.10 vs. 0.26 +/- 0.07, p = 0.001). The left and right ventricular Tei indexes were considered abnormal in 48% and 28% of the chagasic patients, respectively.

Conclusion: Chagasic patients with no apparent heart disease present early alterations of the right and left ventricles.

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Source
http://dx.doi.org/10.1590/s0066-782x2007001800006DOI Listing

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